Publications by authors named "P A Segers"
Subjects with amputation of the lower limbs are at increased risk of cardiovascular mortality and morbidity. We hypothesize that amputation-induced alterations in the arterial tree negatively impact arterial biomechanics, blood pressure and flow behavior. These changes may interact with other biological factors, potentially increasing cardiovascular risk.
View Article and Find Full Text PDFArticle Synopsis
- Systemic arterial properties play a crucial role in determining clinical outcomes and variations in patients with degenerative calcific aortic stenosis (AS), yet many previous studies overlooked pulsatile pressure-flow relations as a critical assessment method.
- A retrospective study of 135 AS patients examined the relationship between pulsatile load and risk of mortality and heart failure hospital admissions using advanced modeling techniques.
- Results show that pressure-dependent total arterial compliance is a significant predictor of mortality and adverse heart failure events, outperforming traditional measures of arterial load, suggesting that understanding arterial wall pressure can better identify high-risk patients.
Radiofrequency ablation is a promising technique for arrhythmia treatment in horses. Due to the thicker myocardial wall and higher blood flow in horses, it is unknown if conventional radiofrequency settings used in human medicine can be extrapolated to horses. The study aim is to describe the effect of ablation settings on lesion dimensions in equine myocardium.
View Article and Find Full Text PDF: Mitral regurgitation (MR) affects millions worldwide, necessitating timely intervention. There are significant clinical challenges in the conservative management of MR, leaving a knowledge gap regarding the impact of multidisciplinary decision-making on treatment outcomes. This study aimed to provide insights into the impact of multidisciplinary decision-making on the survival outcomes of MR patients, focusing on conservative approaches.
View Article and Find Full Text PDFObjectives: Myocardial ischaemia following coronary artery bypass grafting (CABG) is a potentially devastating complication. Nevertheless, the incidence, aetiology and prognostic relevance of unplanned coronary angiography (uCAG) remain understudied. We aimed to investigate the prevalence and outcome of patients undergoing urgent, uCAG in the postoperative period following CABG.
View Article and Find Full Text PDF