Publications by authors named "P A Saunders"

Study Question: How does pre-diagnosis use of hospital care differentiate between women later diagnosed with endometriosis and age-matched controls without a diagnosis?

Summary Answer: Women with hospital-diagnosed endometriosis had more frequent hospital contacts in the 10 years leading up to the diagnosis compared to women without a diagnosis of endometriosis, and the contacts were related to registered diagnoses in nearly all of the included ICD-10 chapters for the entire period.

What Is Known Already: Only a few studies have investigated the utilization of health care among women with endometriosis in the time before diagnosis, but current research shows that women with endometriosis have a higher utilization compared to women without diagnosed endometriosis. To our knowledge, no study has investigated the type of contact related to the higher utilization by using the ICD-10 diagnoses registered to the hospital contact.

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British Army basic training (BT) and initial trade training (ITT) enable personnel to develop role-related physical capability to perform in-service job-roles. The study aimed to compare physical performance of trainees (completing ITT) and trained soldiers, on a series of gym-based fitness tests and representative military tasks. A total of 316 British Army personnel [68 trainees (63 men: 22 ± 3 years, 71.

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Endometriosis is a common, chronic, incurable condition the hallmark of which is the presence of lesions (tissue resembling endometrium) in sites outside the womb, with symptoms including chronic debilitating pain and fatigue. However, current therapeutic options are limited. Recent advances in our understanding of the mechanisms that contribute to the development of lesions and pain experience in endometriosis as well as surveys of patients have increased interest in testing recently approved formulations containing cannabidiol (CBD) in this patient group.

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Article Synopsis
  • Genetic variation in immune responses, particularly related to HLA and KIR genes, influences how First Nations peoples are affected by infectious diseases.
  • HLA-A24:02 and the KIR3DL1 receptor have evolved in First Nations populations, showcasing a significant adaptation through natural selection.
  • The KIR3DL1114 allele, unique to Oceania, demonstrates a strong interaction with HLA-A24:02, which enhances immune response, thus highlighting the importance of immunogenetic studies in understanding disease susceptibility.
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This qualitative study analyzed how Chinese American (CA) and non-Hispanic White (NHW) breast cancer patients and their oncologists communicated about patients' emotional concerns. Data included twenty-four recordings of clinical encounters between oncologists and four CA and eight NHW women with a new breast cancer diagnosis between 2013 and 2015. Using an interactional sociolinguistics approach to discourse analysis, we examined how CA and NHW patients and their oncologists initiated conversations about patients' emotions.

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