Publications by authors named "P A Rosen"
Abutment screw loosening is the most common complication in single implant-supported crowns, typically remedied by simply reattaching the restoration, preferably using a new abutment screw. The internal aspect of the implant along with any other components should be decontaminated before reconnection. This clinical report provides information on the appropriate management of the decontamination process, as well as evidence of the foreign material found within the implant body.
View Article and Find Full Text PDFhas emerged as a nonpathogenic surrogate for , the causative agent of melioidosis, and an important Gram-negative model bacterium for studying the biosynthesis and regulation of secondary metabolism. We recently reported that subinhibitory concentrations of trimethoprim induce vast changes in both the primary and secondary metabolome of . In the current work, we show that the folate biosynthetic enzyme FolE2 is permissive under standard growth conditions but essential for in the presence of subinhibitory doses of trimethoprim.
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- The study evaluated the safety and effectiveness of reconstructing alveolar bone while removing implants due to advanced peri-implantitis in patients looking to replace failed implants for aesthetic or functional reasons.
- A mix of xenograft and autogenous bone was used along with a barrier membrane to regenerate bone, with radiographic assessments conducted before and after the procedure.
- Results showed significant improvements in alveolar ridge width and height, with a large percentage of implants maintaining health after follow-up, indicating the method is safe and effective for developing implant sites.
We have developed electrochemical bandage (e-bandage) prototypes that generate the reactive oxygen species hypochlorous acid (HOCl) or hydrogen peroxide (HO) for potential use to treat biofilm-infected wounds in humans. We have shown that both e-bandage-generated HOCl and HO kill biofilms in vitro and in infected wounds on mice, with the former being more active in vitro. The HO-generating e-bandage, more so than the HOCl-generating e-bandage, was associated with improved healing of infected wounds.
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- The study aimed to compare how well the Modified Frailty Index and the Modified Surgical Apgar scores predict postoperative outcomes, specifically complications and mortality, in head and neck cancer patients.
- The analysis involved 723 patients who underwent major surgeries from 2012 to 2015, with results showing that both scoring systems were significantly linked to 30-day complications, but the Modified Surgical Apgar score was more effective.
- Ultimately, while both scores are valuable for assessing patient risk, the Modified Surgical Apgar score provided better predictive power, and using them together did not enhance accuracy significantly.