Publications by authors named "P A Noseworthy"

Article Synopsis
  • Differentiating between ventricular tachycardia (VT) and supraventricular wide tachycardia (SWCT) using 12-lead ECG is challenging and has traditionally depended on manual interpretation, which can be limited by the user's expertise.
  • Recent research has introduced automated algorithms that may offer improved accuracy over manual methods, but there has been little direct comparison between these two approaches.
  • A study by LoCoco et al. (2024) evaluated the effectiveness of traditional manual ECG differentiation methods against five automated algorithms, analyzing 213 ECGs to assess their diagnostic performance.
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Background: Wide QRS complex tachycardia (WCT) differentiation into ventricular tachycardia (VT) and supraventricular wide complex tachycardia (SWCT) remains challenging despite numerous 12-lead electrocardiogram (ECG) criteria and algorithms. Automated solutions leveraging computerized ECG interpretation (CEI) measurements and engineered features offer practical ways to improve diagnostic accuracy. We propose automated algorithms based on (i) WCT QRS polarity direction (WCT Polarity Code [WCT-PC]) and (ii) QRS polarity shifts between WCT and baseline ECGs (QRS Polarity Shift [QRS-PS]).

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Background: Multimorbidity is common in patients with atrial fibrillation (AF), yet comorbidity patterns are not well documented.

Methods: The prevalence of 18 chronic conditions (6 cardiometabolic, 7 other somatic, 5 mental health) was obtained in patients with new-onset AF from 2013-2017 from a 27-county region and controls matched 1:1 on age, sex, and county of residence. For AF patients and controls separately, clustering of conditions and co-occurrence beyond chance was estimated (using the asymmetric Somers' D statistic), overall and for ages <65, 65-74, 75-84, and ≥85 years.

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Article Synopsis
  • - AEF is an uncommon but serious complication that can occur after PVI procedures.
  • - The presence of free air in the left atrium or pericardium seen on chest CT helps confirm a diagnosis of AEF following PVI.
  • - Standard treatment for AEF is urgent surgical repair, and potential complications can include strokes caused by emboli.
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Background: The determination of left ventricular diastolic function (LVDF) in patients with significant (≥moderate) mitral regurgitation (MR) poses a complex challenge. We recently validated an artificial intelligence-enabled electrocardiogram (AI-ECG) algorithm to estimate LVDF.

Objectives: This study sought to evaluate the risk of all-cause mortality across AI-ECG LVDF-derived myocardial disease (MD) grades in MR.

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