Emotion Regulation Difficulties as a Mediator Between Relationship Satisfaction Predicting Depressive Symptom Trajectories Among Couples in Couple Therapy.

Although adults with depression struggle to effectively emotionally regulate themselves, these findings are limited to one partner in a romantic relationship, community samples, and cross-sectional designs. Hence, we aimed to address these gaps in the literature by investigating emotion regulation difficulties as a predictor of change in depression among couples in couple therapy. Additionally, we aimed to investigate whether emotion regulation difficulties mediated the well-established association between relationship satisfaction and changes in depression of couples in couple therapy.

Iron, lipid peroxidation and ferroptosis play pathogenic roles in atherosclerosis.

Oxidation of lipids, excessive cell death and iron deposition are prominent features of human atherosclerotic plaques. While extensive research has established the detrimental roles of lipid oxidation and apoptosis in atherosclerosis development, the involvement of iron in atherogenesis is not yet fully understood. With the emergence of an iron-dependent form of cell death termed ferroptosis, new attention has been brought to the complex interplay among iron, ferroptosis and atherosclerosis.