Publications by authors named "P A Modesti"
Structural and Functional Remodeling for Elite Cyclists During Exercise; Pressure Volume Loops and Hemodynamic Forces Analysis.
Am J Physiol Heart Circ Physiol
January 2025
The study was designed to investigate the pattern of intraventricular Hemo-Dynamic Forces (HDF) and myocardial performance during exercise in Elite Cyclists (EC). Transthoracic stress echocardiography was performed on nineteen EC and thirteen age-matched sedentary controls (SC) at three incremental exercise intensities based on Heart Rate Reserve (HRR). Left Ventricular (LV) HDF were computed from echocardiography long-axis data sets using a novel technique based on endocardial boundary tracking, both in apex-base and latero-septal directions.
View Article and Find Full Text PDFAssessing Energy Availability and Glucose Dynamics in Adolescent Cyclists: Implications for Nutritional Interventions During the Competitive Season.
Nutrients
November 2024
Article Synopsis
- * Findings revealed that while 100% of cyclists were in a state of low energy availability (LEA) at baseline, using individual nutritional interventions significantly reduced this to 14%, unlike the carbohydrate supplementation which had minimal impact.
- * Overall, factors like training load and body composition affected LEA, but the hot environment did not have a significant effect, highlighting the need for better nutritional education for young athletes.
Article Synopsis
- - Subclinical hypothyroidism (SH) is a condition marked by elevated serum TSH levels with normal free T4, affecting 0.6% to 1.8% of adults, and has been linked to worse outcomes in heart failure patients.
- - A study analyzed 277 heart failure patients, with 23 having SH, and found no significant demographic or health differences between those with SH and those who were euthyroid (normal thyroid function).
- - Results indicated that SH is an independent predictor of cardiovascular mortality, emphasizing the need for thyroid testing in heart failure patients to potentially enhance their treatment and outcomes.
Biological aging, characterized by changes in metabolism and physicochemical properties of cells, has an impact on public health. Environment and lifestyle, including factors like diet and physical activity, seem to play a key role in healthy aging. Several studies have shown that regular physical activity can enhance antioxidant defense mechanisms, including the activity of enzymes such as superoxide dismutase (SOD), catalase, and glutathione peroxidase.
View Article and Find Full Text PDF