A high-resolution in situ X-ray diffraction study of mineral transitions due to post-hydration heating in CM chondrite meteorites.

Abstract: The effects of post-hydration heating over a broad range of temperatures are evident in many Mighei-like carbonaceous (CM) chondrites as a variety of mineral transitions. To better understand these processes and how a CM chondrite's starting composition may have affected them, we experimentally heated two meteorites with different degrees of aqueous alteration, Allan Hills 83100 and Murchison, at 25 °C temperature steps from 200 °C to 950 °C and 300 °C to 750 °C, respectively. During heating, synchrotron in situ X-ray diffraction patterns were collected.

Sex-specific mechanisms of cerebral microvascular BK dysfunction in a mouse model of Alzheimer's disease.

Introduction: Cerebrovascular dysfunction occurs in Alzheimer's disease (AD), impairing hemodynamic regulation. Large conductance Ca-activated K channels (BK) regulate cerebrovascular reactivity and are impaired in AD. BK activity depends on intracellular Ca (Ca sparks) and nitro-oxidative post-translational modifications.

Co-creating an Indigenous-led virtual health services model for Indigenous Australians living with chronic disease.

Objective: To describe the co-design process and understand consumer perspectives of a virtual health services (VHS) model of primary healthcare delivery, for Indigenous Australians with chronic disease and living in regional, rural, and remote Queensland.

Design: Using decolonising methodologies, the study used an Indigenous consensus method to undertake the co-design process and generate findings. For analysis, a qualitative interpretive-description framework was applied.

Conditional generative diffusion deep learning for accelerated diffusion tensor and kurtosis imaging.

Purpose: The purpose of this study was to develop DiffDL, a generative diffusion probabilistic model designed to produce high-quality diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) metrics from a reduced set of diffusion-weighted images (DWIs). This model addresses the challenge of prolonged data acquisition times in diffusion MRI while preserving metric accuracy.

Methods: DiffDL was trained using data from the Human Connectome Project, including 300 training/validation subjects and 50 testing subjects.

Comparative Analysis of Antibiotic Prophylaxis Guidelines in Cardiac Surgery: A Survey in Czechia and Slovakia.

Objectives: Surgical site infections (SSIs) in cardiac surgery significantly impact patient outcomes. This study examines cardiac antimicrobial prophylaxis guidelines in Czech and Slovak hospitals, crucial for reducing SSI incidence.

Methods: An electronic survey was conducted across cardiac surgery departments in both countries, focusing on surgical antibiotic prophylaxis (SAP) protocols, antibiotic choices, dosages, timing, and postoperative infection rates.