Effective BCDNet-based breast cancer classification model using hybrid deep learning with VGG16-based optimal feature extraction.

Problem: Breast cancer is a leading cause of death among women, and early detection is crucial for improving survival rates. The manual breast cancer diagnosis utilizes more time and is subjective. Also, the previous CAD models mostly depend on manmade visual details that are complex to generalize across ultrasound images utilizing distinct techniques.

LCMS Detection and Characterization of In Vitro Metabolites of Isotonitazene, a Targeted Strategy for Novel Psychoactive Substance Control in Camel Racing.

Rationale: The use of benzimidazole-class novel psychoactive substances has significantly increased worldwide raising concerns about potential misuse and doping in animal sports such as camel racing. Understanding the metabolism of these substances is critical for developing reliable detection methods to ensure fair competition and animal welfare.

Methods: In vitro studies were conducted using homogenized camel liver samples to replicate metabolic processes.

Epidermal Growth Factor Receptors Unveiled: A Comprehensive Survey on Mutations, Clinical Insights of Global Inhibitors, and Emergence of Heterocyclic Derivatives as EGFR Inhibitors.

Mutations that overexpress the epidermal growth factor receptor (EGFR) are linked to cancers like breast (15-20%), head and neck (10-15%), colorectal (5-8%), and non-small cell lung cancer (10-50%), especially in East Asian populations. EGFR activation stimulates "RAS/RAF/MEK/ERK, PI3K/Akt, and MAPK" pathways, which enhance cell division, survival, angiogenesis, and tumor growth while inhibiting apoptosis and metastasis. Secondary mutations (e.

Comparative investigation of structural properties and biological applications of chemical and biogenic synthesis of zirconium dioxide (ZrO) nanoparticles using Passiflora edulis.

Over the last decade, the environmental and wellness cost of antibiotic drug resistance to the societies have been astounding and require urgent attention Metal oxide nanomaterials have been achieved a pull-on deal with its entire applications in biological and photocatalytic applications. The present study conducts a comparative investigation on chemical and biogenic synthesis of zirconium dioxide (ZrO) nanoparticles aimed at enhancing their efficacy in their applications. The plant extract of Passiflora edulis act as a reducing and capping properties offering a sustainable and eco-friendly alternative.

In vitro and In silico investigation deciphering novel antifungal activity of endophyte Bacillus velezensis CBMB205 against Fusarium oxysporum.

Endophytes from medicinal plants are potential biocontrol agents against Fusarium oxysporum f. sp. cubense (Foc), which is the causative fungus of banana wilt disease.