Publications by authors named "P A Koul"
Introduction: Previous population-based studies, mainly from high-income countries, have shown that a higher forced vital capacity (FVC) is associated with a lower risk of developing cardiometabolic diseases. The aim of this study was to assess the longitudinal association between spirometry measures and the onset of cardiometabolic diseases across sites in low-income, middle-income and high-income countries.
Methods: The study population comprised 5916 individuals from 15 countries participating in the Burden of Obstructive Lung Disease baseline and follow-up assessments.
Acute exacerbations of COPD (ECOPD) are an important event in the life of a COPD patient as it causes significant deterioration of physical, mental, and social health, hastens disease progression, increases the risk of dying and causes a huge economic loss. Preventing ECOPD is therefore one of the most important goals in the management of COPD. Before the patient is discharged after hospitalization for ECOPD, it is crucial to offer an evidence-based care bundle protocol that will help minimize the future risk of readmissions and death.
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- Spirometry is a test used to evaluate lung function by comparing it to normal levels in healthy non-smokers, focusing on metrics like forced vital capacity (FVC) and the FEV/FVC ratio.
- The study analyzed data from over 14,000 participants aged 40 and older across 41 sites, revealing regional differences in FVC tied to factors like age and height, categorized into four regions: Europe/richer countries, Near East, Africa, and Far East.
- Findings showed significant regional variations in FVC values between men and women, particularly in Europe compared to the Far East, but minimal differences in the FEV/FVC ratio across regions.
Introduction: Platelet function testing using serial VerifyNow P2Y12 platelet reactivity units (PRUs) is established for guiding clopidogrel antiplatelet therapy in cerebral aneurysm stenting procedures. However, for ticagrelor, the impact of serial PRU testing and the identification of safe PRU ranges remains unexplored.
Methods: Flow diversion stenting ( = 232) and stent-assisted coiling procedures ( = 83) performed 05/2017-12/2021 were reviewed.