Transplantation Referral Patterns for Patients with Newly Diagnosed Higher-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia at Academic and Community Sites in the Connect® Myeloid Disease Registry: Potential Barriers to Care.

Hematopoietic stem cell transplantation (HCT) is indicated for patients with higher-risk (HR) myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Age, performance status, patient frailty, comorbidities, and nonclinical factors (eg, cost, distance to site) are all recognized as important clinical factors that can influence HCT referral patterns and patient outcomes; however, the proportion of eligible patients referred for HCT in routine clinical practice is largely unknown. This study aimed to assess patterns of consideration for HCT among patients with HR-MDS and AML enrolled in the Connect® Myeloid Disease Registry at community/government (CO/GOV)- or academic (AC)-based sites, as well as to identify factors associated with rates of transplantation referral.

Corrigendum to "Predicting verbal reasoning from virtual community membership in a sample of Russian young adults" [Heliyon 8 (6) (2022) e09664].

[This corrects the article DOI: 10.1016/j.heliyon.

Predicting verbal reasoning from virtual community membership in a sample of Russian young adults.

Predicting personality traits from social networking site profiles can help to assess individual differences in verbal reasoning without using long questionnaires. Inspired by earlier studies, which investigated whether abstract-thinking ability are predictable by social networking sites data, we used supervised machine learning to predict verbal-reasoning ability based on a proposed set of features extracted from virtual community membership. A large sample (N = 3,646) of Russian young adults aged 18-22 years approved access to the data from their social networking accounts and completed an online test on verbal reasoning.

Longitudinal health-related quality of life in first-line treated patients with chronic lymphocytic leukemia: Results from the Connect CLL Registry.

Health-related quality of life (HRQoL) in patients with chronic lymphocytic leukemia (CLL) is important in guiding treatment decisions. However, the impact of CLL treatment initiation on HRQoL is unclear. We assessed HRQoL using the FACT-Leu and EQ-5D-3L questionnaires in the Connect CLL Registry, a large, US-based, multicenter, prospective observational study of CLL patients enrolled between 2010 and 2014, prior to the introduction of novel therapies.