[Heparin therapy of pregnant women with placental insufficiency].

In the presence of low-dosage administrations of heparin the system of hemostasis was studied in 50 pregnant females with placental failure and the chronic DIC syndrome. The efficacy of the treatment conducted was assessed with regard to the revealed levels of coagulation natural inhibitors, the products of fibrinogen-fibrin degradation, the degree of thrombocytic functional recovery and stabilization of the chronometric values of coagulation. The latter parameters considered together with the levels of heparinemia served as the criteria for the safety of the drug dosages employed.

[Monitoring of platelet activity as a basis for the use of antiaggregants in placental insufficiency].

Platelet hemostatic component was studied in 20 pregnant patients with placental insufficiency. Schedules of antiaggregant treatment have been proposed with respect to the magnitude of abnormal platelet activation. It is concluded that platelet monitoring is essential for the choice of an optimum treatment regimen.