Publications by authors named "P A Kalinin"

Pituitary carcinoma (metastatic neuroendocrine tumor of the pituitary gland) is the pituitary tumor with confirmed craniospinal and/or systemic metastases. These tumors are extremely rare accounting for only 0.1% to 0.

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  • Craniopharyngiomas (CP) are benign tumors located near key brain structures, and their surgical removal depends on their specific anatomical positioning.
  • A literature review identified 21 studies analyzing the topographic and anatomical classifications of CP, focusing on relationships to critical areas like the hypothalamic-pituitary axis and third ventricle.
  • Understanding these classifications is essential for determining the appropriate surgical methods and improving diagnostic techniques, particularly through advanced imaging like high-resolution MRI.
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  • Craniopharyngioma (CP) is a benign tumor located mainly in the brain's chiasmatic-sellar region, with two main types: adamantinoma-like (ACP) and papillomatous (PCP), the latter mostly affecting adults.
  • The study aimed to determine the disease-free survival in adults with newly diagnosed CP based on the quality of tumor removal and the effectiveness of irradiation, using data from 398 patients over a decade.
  • Results showed that total tumor resection significantly lowers recurrence risk, while stereotactic irradiation after incomplete resection also yields favorable outcomes, with PCPs being less aggressive and less likely to recur after complete removal.
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Unlabelled: Dysembryoplastic neuroepithelial tumor (DNET) is a benign mixed neuronal-glial neoplasm (WHO grade 1). DNET is most often localized in temporal lobes and found in children and young people with epilepsy. There a few cases of DNET in ventricular system with dissemination along the ependyma in the world literature.

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Despite slow growth of most pituitary tumors and high rates of total resection and/or effective therapy, pituitary neoplasms are characterized by aggressive behavior with high growth rate, frequent relapses and resistance to standard treatments in 10% of cases. In modern WHO classifications of tumors of the central nervous system, endocrine and neuroendocrine tumors, the authors propose the definition «pituitary neuroendocrine tumor» instead of previous «pituitary adenoma» and «metastasizing pituitary neuroendocrine tumor» instead of «pituitary carcinoma». Currently, there are no effective prognostic markers of aggressive tumors.

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