Publications by authors named "P A Grimont"

The current study describes a novel species with the strain name ERMR1:05 isolated from the forefield soil of East Rathong Glacier in West Sikkim Himalaya (India). The isolate was facultatively anaerobic, gram-stain negative, non-spore-forming, rod-shaped, and oxidase negative. Whole-genome-based bacterial core gene phylogenetic analysis placed the strain in the genus Rahnella, well separated from Rouxiella spp.

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The genus Serratia has been studied for over a century and includes clinically-important and diverse environmental members. Despite this, there is a paucity of genomic information across the genus and a robust whole genome-based phylogenetic framework is lacking. Here, we have assembled and analysed a representative set of 664 genomes from across the genus, including 215 historic isolates originally used in defining the genus.

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Article Synopsis
  • Atrioventricular valve surgery carries a risk of heart attacks due to its proximity to the coronary arteries, and the study aimed to pinpoint high-risk zones on the mitral and tricuspid valves.
  • Researchers examined 25 extracted hearts to measure distances between artery and valve using a clock-face model to categorize proximity levels as very high, high, or relative, based on distance measurements.
  • The study found specific high-risk zones: for the mitral valve between "7:30" and "10:00" and for the tricuspid valve between "1:30" and "3:00," which can help guide surgeons to avoid damaging the coronary arteries during procedures.
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Latin America has experienced two of the largest cholera epidemics in modern history; one in 1991 and the other in 2010. However, confusion still surrounds the relationships between globally circulating pandemic clones and local bacterial populations. We used whole-genome sequencing to characterize cholera across the Americas over a 40-year time span.

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Article Synopsis
  • The seventh cholera pandemic has significantly impacted Africa, with its origins and spread not fully understood.
  • Researchers analyzed genomic data from 1070 cholera O1 isolates across 45 African countries over 49 years, finding that past epidemics came from a single expanded lineage introduced multiple times since 1970.
  • Recent introductions consisted of drug-resistant sublineages from Asia, emphasizing the need for targeted cholera control measures based on the identified patterns of spread.
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