Publications by authors named "P A Frith"
Article Synopsis
- "Pre-COPD" refers to individuals at high risk of developing Chronic Obstructive Pulmonary Disease (COPD) but who do not show typical signs of airflow obstruction; the study emphasizes the need for new ways to identify these at-risk groups, especially among younger people.
- The study utilized data from the Tasmanian Longitudinal Health Study, examining lung function and respiratory symptoms of participants at ages 45 and 53, concluding that a specific FEV/FVC score can effectively predict the risk of developing COPD.
- Findings show that individuals with a pre-BD FEV/FVC score below -1.264 had a 36-fold increased risk of COPD, highlighting the importance of including this spirometry measure in
(1) Background: Most controlled trials of cognitive behavior therapy (CBT) in people living with chronic obstructive pulmonary disease (COPD) have targeted anxiety and depression. (2) Methods: This pragmatic randomized controlled trial explored whether a comprehensive pulmonary rehabilitation program (CPRP) with CBT for breathlessness or social group control (CPRP + SC) significantly improved health outcomes. (3) Results: People with moderate-to-severe COPD were block randomized (CPRP + CBT = 52 or CPRP + SC = 49).
View Article and Find Full Text PDFBackground: Interest in lifetime lung function trajectories has increased in the context of emerging evidence that chronic obstructive pulmonary disease (COPD) can arise from multiple disadvantaged lung function pathways, including those that stem from poor lung function in childhood. To our knowledge, no previous study has investigated both obstructive and restrictive lifetime patterns concurrently, while accounting for potential overlaps between them. We aimed to investigate lifetime trajectories of the FEV/forced vital capacity (FVC) ratio, FVC, and their combinations, relate these combined trajectory groups to static lung volume and gas transfer measurements, and investigate both risk factors for and consequences of these combined trajectory groups.
View Article and Find Full Text PDFBackground: Prematurity has been linked to reduced lung function up to age 33 years, but its long-term effects on lung function and chronic obstructive pulmonary disease (COPD) are unknown. To address this question, we investigated associations between prematurity, lung function, and COPD in the sixth decade of life using data from the Tasmanian Longitudinal Health Study (TAHS).
Methods: Data were analysed from 1445 participants in the TAHS.
Background: Classifying individuals at high chronic obstructive pulmonary disease (COPD)-risk creates opportunities for early COPD detection and active intervention.
Objective: To develop and validate a statistical model to predict 10-year probabilities of COPD defined by post-bronchodilator airflow obstruction (post-BD-AO; forced expiratory volume in 1 s/forced vital capacity<5th percentile).
Setting: General Caucasian populations from Australia and Europe, 10 and 27 centres, respectively.