Publications by authors named "P A Dyer"
Article Synopsis
- Leishmania parasites are spread to mammals (like humans) by sandfly bites and can infect different types of immune cells, but the immune response differs between mice and humans.
- In a study focused on human infection, researchers analyzed immune responses using fresh blood samples and flow cytometry, discovering that neutrophils and monocytes make up the majority of cells responding in the initial hours.
- Interestingly, the study also identified a significant presence of CD4 T cells among the leukocytes, suggesting they might play a role in the early stages of Leishmania infection.
Background: Aggressive metastasis directed treatment of extracranial oligometastatic breast cancer with the aim of increasing disease-free survival has emerged as a new potential treatment paradigm, however there is currently a lack of data to assist in identifying the subset of patients who will potentially benefit most. This single-institute retrospective cohort study aimed to evaluate survival outcomes for patients with a solitary extracranial metastasis from breast cancer and to assess for significant prognostic factors.
Methods And Materials: Medical records of 70 female breast cancer patients with a solitary extracranial metastasis actively managed at the Peter MacCallum Cancer Centre (PMCC) Melbourne Campus between 2000 and 2019 were reviewed.
Members of the lichen-forming fungal genus are known to occur in cold polar and high altitudinal environments. Two new species, and , are now described from the high altitude Deosai Plains, Pakistan, based on phenotypic, multigene phylogenetic and chemical evidence. Phenotypically, is characterised by orbicular light-brown thalli 1.
View Article and Find Full Text PDFPenicillium roqueforti is used worldwide in the production of blue-veined cheese. The blue-green colour derives from pigmented spores formed by fungal growth. Using a combination of bioinformatics, targeted gene deletions, and heterologous gene expression we discovered that pigment formation was due to a DHN-melanin biosynthesis pathway.
View Article and Find Full Text PDFEmergency and acute hospital services in England are under increasing pressure. The aim of this study was to investigate the association between key case-mix indicators and outcomes for adults admitted to hospital with an acute medical condition in England. All patients aged ≥16 years admitted to hospital in England as an acute unselected medical admission and who survived to discharge during the financial year 2021-2022 were included.
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