Digital solutions for migrant and refugee health: a framework for analysis and action.

Digital technologies can help support the health of migrants and refugees and facilitate research on their health issues. However, ethical concerns include security and confidentiality of information; informed consent; how to engage migrants in designing, implementing and researching digital tools; inequitable access to mobile devices and the internet; and access to health services for early intervention and follow-up. Digital technical solutions do not necessarily overcome problems that are political, social, or economic.

Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort.

Background: Cirrhosis has been pointed out as a clinical entity that leads to worse clinical prognosis in COVID-19 patients. However, this concept is controversial in the literature. We aimed to evaluate clinical outcomes by comparing patients with cirrhosis to those without cirrhosis in a Brazilian cohort.

Structural and functional insights into recombinant β-glucosidase from Thermothelomyces thermophilus: Cello-oligosaccharide hydrolysis and thermostability.

β-glucosidases (BGLs) are key enzymes in the depolymerization of cellulosic biomass, catalyzing the conversion of cello-oligosaccharides into glucose. This conversion is pivotal for enhancing the production of second-generation ethanol or other value-added products in biorefineries. However, the process is often cost-prohibitive due to the high enzyme loadings required.

Educational intervention in first aid for early childhood education professional: a quasi-experimental study.

Objective: To evaluate the effect of a first aid educational intervention on the aptitude, knowledge, and practices of professionals in early childhood education.

Method: Quasi-experimental study of the pre and post-test type carried out in the brazilian municipality of Três Lagoas, MS. It was developed in three stages: 1) application of an online instrument to assess aptitude, knowledge, and practices about situations that require first aid; 2) educational intervention, with four theoretical meetings online and a face-to-face meeting with practical training; 3) reapplying the questionnaire.

An Acute Discovery of Fourth Ventricle Outflow Obstruction in Previously Idiopathic Chronic Hydrocephalus: A Case Report.

Hydrocephalus is the disruption of cerebral spinal fluid homeostasis, representing a common neurosurgical illness. Up to 10% have no identifiable cause, with fourth ventricle outflow obstruction (FVOO) being an extremely rare subtype. A 31-year-old male with a history of idiopathic hydrocephalus for over 10 years with the need for a ventriculoperitoneal shunt had shown progressively enlarged tetraventricular ventriculomegaly.