Publications by authors named "P A Cistulli"

Despite decades of research, defining insomnia remains challenging due to its complex and variable nature. Various diagnostic systems emphasize the chronic nature of insomnia and its impact on daily functioning, relying heavily on patient self-reporting due to limitations in objective measures like polysomnography (PSG). Discrepancies between subjective experiences and objective PSG results highlight the need for more nuanced approaches, such as electroencephalogram (EEG) spectral analysis, which reveals distinct patterns of high-frequency activity in individuals with insomnia.

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  • - This study investigates how irregular sleep patterns affect the risk of major cardiovascular events (MACE) among adults aged 40-79, using data from wrist-worn accelerometers to measure sleep regularity.
  • - Results from over 72,000 participants show that those with irregular sleep are at a significantly higher risk of MACE, with the risk increasing as sleep regularity decreases.
  • - Importantly, while adequate sleep duration can reduce MACE risk for moderately irregular sleepers, it doesn't offset the high risk for those with irregular sleep, highlighting the need to consider sleep regularity in health guidelines.
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  • - Sleep-disordered breathing includes various conditions like obstructive sleep apnea (OSA), central sleep apnea, and sleep-related hypoventilation, each with unique diagnostic criteria and treatment methods.
  • - Dental practitioners should understand more than just OSA, as different sleep disorders require different management approaches.
  • - This review paper highlights how to diagnose and manage the common types of sleep-disordered breathing, emphasizing the dental perspective in treatment.
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  • * Out of 66 ACS patients, 94% were diagnosed with OSA, with 68% having moderate-to-severe cases; however, common screening questionnaires were not effective in identifying these severe cases.
  • * Although increased arterial stiffness and carotid intima-media thickness were found in patients with moderate-to-severe OSA, these findings were not statistically significant after adjusting for other factors, indicating potential limitations in the study's conclusions.
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