Publications by authors named "P A Caruso"
Introduction: Post-stroke cognitive impairment (PSCI) and dementia affect short- and long-term outcome after stroke and can persist even after recover from a physical handicap. The process underlying PSCI is not yet fully understood. Transcranial Doppler ultrasound (TCD) is a feasible method to investigate cerebrovascular aging or dementia, through the pulsatility index (PI), the cerebrovascular reactivity (e.
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- Acute decompensated pulmonary arterial hypertension (ADPH) leads to right heart failure, posing a high risk of mortality, making the assessment of mortality rates and life-sustaining therapies essential for patient management.
- A systematic review of 25 studies showed ICU mortality at 29% and hospital mortality at 38%, with higher mortality (45%) among patients needing extracorporeal membrane oxygenation (ECMO). Additional treatments like inotropes and vasopressors also indicated increased mortality rates.
- The study highlights the variability in ADPH mortality related to different clinical settings and therapies, emphasizing the importance of these findings for clinical practice and discussions with patients and their families.
Article Synopsis
- The review focuses on understanding gender differences in the risk factors and mechanisms of both Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D), as well as prediabetes, to improve early diagnosis and prevention strategies.
- Gender differences are notable; T1D tends to affect males more significantly after puberty, while T2D’s risk factors are influenced by body composition and lifestyle differences between genders.
- Findings suggest that recognizing these gender-specific risk factors is crucial for developing targeted prevention and screening programs to decrease the incidence of diabetes.*
Purpose: The incidence and risk factors associated with radiation-induced Moya-Moya Syndrome (RIMMS) in pediatric brain tumor patients treated with proton radiotherapy (PRT) remain poorly understood. The objective of this study was to determine the incidence of RIMMS in the setting of CNS proton radiotherapy (PRT) in a pediatric cohort and assess its relationship with dose to the Circle of Willis (COW) or optic chiasm (OC).
Methods & Materials: We performed a retrospective review of pediatric brain tumor patient treated with intracranial PRT (1995-2021).