Publications by authors named "P A Bron"

Article Synopsis
  • Carotenoids are important pigments found in plants and algae that have antioxidant and anti-inflammatory benefits, and they are also seen in some non-photosynthetic prokaryotes, but their role outside photosynthetic organisms is not well understood.
  • This study analyzed terpenoid biosynthetic gene clusters in the Lactobacillaceae family, identifying crtMN genes related to C30 carotenoid production in 28 species across various genera.
  • The presence of these genes is linked to habitat adaptation, with nomadic and insect-adapted Lactobacillaceae showing higher rates of C30 carotenoid production, which helps them resist UV stress in their environments.*
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Article Synopsis
  • * A study using advanced sequencing techniques found that the skin microbiome in mild AD does not significantly differ in diversity from non-AD patients, and the presence of Staphylococcus aureus remains similar in both groups.
  • * However, certain bacteria were found in higher or lower abundances in mild AD lesions, suggesting that understanding these differences could lead to new diagnostic tools and treatments to help manage this condition early on.
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Dairy industries apply selected lactococcal strains and mixed cultures to produce diverse fermented products with distinctive flavor and texture properties. Innovation of the starter culture functionality in cheese applications embraces natural biodiversity of the Lactococcus species to identify novel strains with alternative flavor or texture forming capacities and/or increased processing robustness and phage resistance. Mobile genetic elements (MGE), like integrative conjugative elements (ICEs) play an important role in shaping the biodiversity of bacteria.

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Chikungunya virus (CHIKV) is a mosquito-borne pathogen responsible for an acute musculoskeletal disease in humans. Replication of the viral RNA genome occurs in specialized membranous replication organelles (ROs) or spherules, which contain the viral replication complex. Initially generated by RNA synthesis-associated plasma membrane deformation, alphavirus ROs are generally rapidly endocytosed to produce type I cytopathic vacuoles (CPV-I), from which nascent RNAs are extruded for cytoplasmic translation.

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Lactococcus lactis is widely applied by the dairy industry for the fermentation of milk into products such as cheese. Adaptation of L. lactis to the dairy environment often depends on functions encoded by mobile genetic elements (MGEs) such as plasmids.

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