Publications by authors named "P A Bovier"
Total correlation spectroscopy (TOCSY) is a key experiment to assign nuclear magnetic resonance (NMR) spectra of complex molecules. Carbon-13 TOCSY experiments are essential to assign signals of protein side chains. However, the performance of carbon-13 TOCSY deteriorates at high magnetic fields since the necessarily limited radiofrequency irradiation fails to cover the broad range of carbon-13 frequencies.
View Article and Find Full Text PDFNuclear magnetic resonance (NMR) is a ubiquitous branch of spectroscopy that can explore matter at the scale of an atom. Significant improvements in sensitivity and resolution have been driven by a steady increase of static magnetic field strengths. However, some properties of nuclei may be more favourable at low magnetic fields.
View Article and Find Full Text PDFRecovering Invisible Signals by Two-Field NMR Spectroscopy.
Angew Chem Int Ed Engl
August 2016
Article Synopsis
- - Nuclear magnetic resonance (NMR) has greatly improved due to stronger magnetic fields, enhancing sensitivity and resolution for complex molecular studies.
- - High magnetic fields can cause line broadening, making it hard to analyze certain chemical compounds, but a new two-field NMR spectrometer helps overcome this issue.
- - This innovative method allows researchers to obtain clearer spectra of small molecules and proteins, enabling better analysis of molecules affected by internal dynamics and enhancing the capabilities of NMR at high fields.