Publications by authors named "P A Botha"
Objective: The study objective was to determine whether adequately delivered bilateral remote ischemic preconditioning is cardioprotective in young children undergoing surgery for 2 common congenital heart defects with or without cyanosis.
Methods: We performed a prospective, double-blind, randomized controlled trial at 2 centers in the United Kingdom. Children aged 3 to 36 months undergoing tetralogy of Fallot repair or ventricular septal defect closure were randomized 1:1 to receive bilateral preconditioning or sham intervention.
Article Synopsis
- * Conducted in 2022, the research involved 97 MSM participants who provided demographic information and underwent testing for various STIs, revealing that 24.7% had an extragenital STI and 9.4% had high syphilis antibody titers.
- * Key risk factors identified for having extragenital STIs included drug use during sex and engaging in condomless receptive anal intercourse with casual partners, highlighting the urgency for regular screening in this population. *
Introduction: Esophago-vascular fistulae in children are almost uniformly fatal with death occurring by exsanguination. We present a single centre series of five surviving patients, a proposal for management and literature review.
Materials And Methods: Patients were identified from surgical logbooks, surgeon recollection and discharge coding data.
Outcomes of the arterial switch for transposition during infancy using a standardized approach over 30 years.
Interdiscip Cardiovasc Thorac Surg
July 2023
Objectives: The aim of this study was to describe the early and late outcomes of the arterial switch for transposition.
Methods: A single-centre retrospective cohort study was conducted to assess the early and late outcomes of arterial switch performed during infancy using a standardized institutional approach between 1988 and 2018, compared by morphological groups.
Results: A total of 749 consecutive patients undergoing arterial switch during infancy were included, 464 (61.
Aim: The aim of this study was to assess the safety and efficacy of long-term milrinone therapy in children with acute decompensated heart failure due to dilated cardiomyopathy (DCM).
Methods: A single-centre retrospective study of all children ≤18 years with acute decompensated heart failure and DCM who received continuous long-term (≥7 consecutive days) intravenous milrinone between January 2008 and January 2022.
Results: The 47 patients had a median age of 3.