Publications by authors named "P A Accorsi"

The global decline of species necessitates intensive conservation efforts, including ex-situ breeding programs to safeguard endangered populations. However, managing welfare and reproduction in zoological gardens can present several challenges. This study aims to explore behaviors and endocrinological responses of two specimens of fossa (Cryptoprocta ferox) under human care.

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Plains zebras are commonly hosted in zoos, but few welfare-related studies are available in the literature. This research aimed to assess the effect of enclosure design on two groups of captive zebras housed at the Giardino Zoologico di Pistoia - GZP (Italy) and Parco Faunistico Valcorba - PFV (Italy) through the analysis of behavior and enclosure use. The groups consisted of an adult pair and a male juvenile at GZP and six adult females at PFV.

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Article Synopsis
  • Large studies and specific electrophysiology techniques have helped identify various SCN2A-epilepsy phenotypes, their genetic connections, and their reactions to sodium channel blockers.
  • One notable presentation of SCN2A variants is benign familial neonatal-infantile seizures (BFNIS), which typically occur within the first 23 months of life and often resolve within two years, sometimes with treatment.
  • A recent case highlights a woman, originally diagnosed with BFNIS in infancy, who experienced additional seizures over 40 years later, suggesting SCN2A-related seizures may have implications in adulthood.
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A heterozygous gain-of-function variant in the acyl-CoA oxidase 1 (ACOX1) gene, c.710A>G (p.Asn237Ser), is known to cause Mitchell syndrome, a very rare progressive disorder characterized by episodic demyelination, sensory polyneuropathy, and hearing loss.

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In veterinary medicine, Cannabis has been used to treat pain conditions, inflammation, and seizures. However, little is known about its effect on dogs' behavior. This preliminary research aims to address this knowledge gap by evaluating the effectiveness of cannabidiol (CBD) oil in canine behavioral therapy.

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