Publications by authors named "Pınar Ozay Nayır"
Article Synopsis
- - Spontaneous regression (SR) refers to the unexpected reduction or disappearance of a tumor without treatment, but it is rare in both breast cancer and other cancer types.
- - The study included two cases of SR but lacked sufficient evidence to clarify the underlying mechanisms, and neither patient showed PD-L1, contradicting its proposed antitumoral role.
- - One patient was the first documented case with Cerb B2 positivity and an early SR period, suggesting that thorough examinations before surgery could increase SR occurrences in breast cancer and aid in understanding the underlying mechanisms.
Evaluation of neurogranin levels in a rat model of diffuse axonal injury.
Acta Neurobiol Exp (Wars)
March 2024
Diffuse axonal injury (DAI), one of the most common and devastating type of traumatic brain injury, is the result of the shear force on axons due to severe rotational acceleration and deceleration. Neurogranin (NRGN) is a postsynaptic protein secreted by excitatory neurons, and synaptic dysfunction can alter extracellular NRGN levels. In this study, we examined NRGN levels in serum and cerebrospinal fluid (CSF) after experimental DAI in terms of their diagnostic value.
View Article and Find Full Text PDFObjective: We compared the breast cancer patients with invasive lobular carcinoma (ILC), invasive ductal carcinoma (IDC) and mixed invasive ductal and lobular carcinoma (IDLC) in terms of clinicopathological and treatment features, metastatic patterns and long-term survival.
Materials And Methods: In a 10 years patient cohort, 3412 patients with unilateral breast carcinoma were enrolled in the study. Tumors were classified histologically according to criteria described by World Health Organization classification.