Publications by authors named "Ozturk L"
Retrospective Evaluation of Anesthesia in Patients Undergoing Surgery after the February 6, 2023 Earthquake in Turkey.
Disaster Med Public Health Prep
January 2025
Throughout human history, numerous natural disasters, particularly earthquakes, have caused significant destruction to civilizations. On February 6, 2023, 2 major earthquakes struck Turkey. The first occurred at 04:17 local time with a magnitude of 7.
View Article and Find Full Text PDFBackground: Hearing loss (HL) is a major public health problem that is significant for mental health and physical conditions. HL may be a potentially modifiable risk factor for poorer mental health outcomes. The study aimed to explore the association between HL, social isolation, anxiety, and depression.
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- The study aimed to evaluate machine learning and deep learning techniques for detecting systemic scleroderma using nailfold capillaroscopy images from patients in the French SCLEROCAP study.
- Machine learning classifiers showed varying performance, with the best results (F1 score of 0.79) achieved using the light gradient boosting model, while deep learning with DenseNet-121 greatly outperformed with an accuracy of 0.94.
- This research highlights the potential of advanced machine learning and deep learning methods for improving the accuracy of systemic scleroderma diagnosis through image analysis.
Preoperative preparation and postoperative care in children in thoracic surgery.
Turk Gogus Kalp Damar Cerrahisi Derg
January 2024
Article Synopsis
- Pediatric patients have unique anatomical and physiological differences from adults, making their anesthesia for thoracic surgery distinctive.
- Proper preoperative preparation, effective tool selection for one-lung ventilation, and good pain management are crucial for improved postoperative care.
- This review will cover the perioperative anesthesia management for these patients, focusing on preoperative steps and the challenges of one-lung ventilation.
The effect of 24-hour sleep deprivation on subjective time perception.
Int J Psychophysiol
October 2023
In this study, we investigated the effect of 24-h total sleep deprivation on subjective time perception. Twenty-five participants aged 18-35 years (13 female and 12 male) were recruited. Time perception and cognitive assessments were performed twice: after a regular night's sleep and following a 24-h sleep deprivation.
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- Saddle block anesthesia (SBA) is commonly used for outpatient anorectal surgeries, and this study compared two doses of hyperbaric bupivacaine to assess their impact on recovery time and block characteristics.
- Patients aged 18 and over were divided into two groups: those receiving 5 mg and those receiving 3 mg of bupivacaine, focusing on discharge times and several secondary outcomes like sensory block duration and side effects.
- Results showed that the 3 mg group had faster recovery with shorter discharge and voiding times, indicating that lower doses of hyperbaric bupivacaine could be a better option for reducing complications and improving patient outcomes.
Vagus nerve signals from the gut to brain carry information about nutrients and drive food reward. Such signals are disrupted by consuming large amounts of high-calorie foods, necessitating greater food intake to elicit a similar neural response. Non-invasive vagus nerve stimulation (nVNS) via a branch innervating the ear is a candidate treatment for obesity in humans.
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- - This study aimed to examine how one night of sleep deprivation impacts cognitive function in healthy young adults aged 18-30.
- - Twenty-one participants were tested on cognitive assessments before and after a night without sleep, compared to a control group that had normal sleep.
- - Results showed no significant changes in cognitive performance due to sleep deprivation, suggesting that a single night without sleep may not significantly affect cognitive abilities in healthy individuals.
Article Synopsis
- This study evaluated the effectiveness of the Sleep Disturbance Scale for Children (SDSC) for Turkish-speaking children by translating and validating the tool.
- A sample of 1903 children aged 5-15 participated, with assessments conducted through questionnaires filled out by their parents.
- The findings highlighted that the Turkish version of SDSC is both valid and reliable, showing high internal consistency and revealing a 4.15% prevalence of sleep disorders, mainly sleep hyperhidrosis.
Article Synopsis
- Recent studies show that sleep deprivation (SD) is a modifiable risk factor for hypertension, but the mechanisms behind this link are not fully understood.
- The study tested how SD affects blood pressure responses in healthy young males through various cardiac stress tests over three consecutive days.
- Results indicated that one night of SD impaired blood pressure reactivity to stress tests, although resting blood pressure levels remained unchanged, emphasizing the role of sleep in blood pressure regulation.
Repeated Doses of Ketamine Affect the Infant Rat Urogenital System.
Drug Des Devel Ther
October 2021
Article Synopsis
- - This study investigates the impact of long-term ketamine use on various organs, specifically focusing on potential damage to the kidneys, testicles, epididymis, and ductus deferens, in addition to the previously known bladder issues.
- - Male Wistar Albino rats were divided into two groups, one receiving ketamine and the other saline, for three weeks, after which their kidney and testicular tissues were analyzed for biochemical and histopathological changes.
- - Results indicated significant kidney and testicular damage in the ketamine group, marked by increased tissue congestion and altered enzyme activity, suggesting further clinical and research exploration is needed regarding the effects of repeated ketamine administration in medical settings.
Feed Composition Differences Resulting from Organic and Conventional Farming Practices Affect Physiological Parameters in Wistar Rats-Results from a Factorial, Two-Generation Dietary Intervention Trial.
Nutrients
January 2021
Article Synopsis
- Recent studies indicate that eating organic food may be linked to lower rates of obesity, cancer, and other diseases, but research supporting these claims is limited.
- A two-generation study with male Wistar rats examined how organic versus conventional feed affected growth, hormone levels, and immune responses, focusing on the impact of synthetic pesticides and fertilizers.
- Results showed significant differences in feed composition based on crop protection methods, leading to notable effects on feed intake, weight gain, and immune function, highlighting the complex interactions between diet and health outcomes.
Four new fulgimides possessing a fluorescent coumarin unit were synthesized from the corresponding fulgides, and their photochromic as well as fluorescence properties were investigated. The open-ring forms of coumarin fulgimides were found to exhibit fluorescence in the visible region. Upon exposure to UV light, the fulgimides were transformed into the nonfluorescent closed-ring forms, which can be reverted to the initial fluorescent open-ring forms on exposure to visible light.
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- The study aimed to assess the impact of wearing FFP3 masks on venous blood gases and subjective symptoms in healthcare professionals.
- After 4 hours of mask usage, venous blood gas levels remained stable, with no significant changes detected.
- Although participants reported various symptoms like headaches and lightheadedness, the overall findings suggested that FFP3 masks were tolerated well without causing major discomfort.
In a preregistered, cross-sectional study, we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0-100 visual analog scales (VAS) for participants reporting a positive (C19+; n = 4148) or negative (C19-; n = 546) COVID-19 laboratory test outcome. Logistic regression models identified univariate and multivariate predictors of COVID-19 status and post-COVID-19 olfactory recovery.
View Article and Find Full Text PDFtVNS Increases Liking of Orally Sampled Low-Fat Foods: A Pilot Study.
Front Hum Neurosci
November 2020
Recently a role for the vagus nerve in conditioning food preferences was established in rodents. In a prospective controlled clinical trial in humans, invasive vagus nerve stimulation shifted food choice toward lower fat content. Here we explored whether hedonic aspects of an orally sampled food stimulus can be modulated by non-invasive transcutaneous vagus nerve stimulation (tVNS) in humans.
View Article and Find Full Text PDFAn amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFBackground: COVID-19 has heterogeneous manifestations, though one of the most common symptoms is a sudden loss of smell (anosmia or hyposmia). We investigated whether olfactory loss is a reliable predictor of COVID-19.
Methods: This preregistered, cross-sectional study used a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness.
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments, such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation, and initial results of a multilingual, international questionnaire to assess self-reported quantity and quality of perception in 3 distinct chemosensory modalities (smell, taste, and chemesthesis) before and during COVID-19.
View Article and Find Full Text PDFPurpose: The aim of our study was to determine guide parameters for clinicians by morphometric assessment of important landmarks on cranium intended for Vidian nerve surgery.
Methods: For the study, 23 half-skull bases, 40 skull bases and 40 skulls were obtained from the Department of Anatomy, Ege University Medicine Faculty. The vertical distances were measured using a digital caliper to the nearest 0.
Objective: We aimed to investigate the effects of recurrent sevoflurane anesthesia on cognitive functions in Alzheimer Disease.
Materials And Methods: Rats were divided into 4 groups as followed: control (Group C), sevoflurane (Group S), Alzheimer's (Group A) and Alzheimer's + sevoflurane (Group AS)]. Cognitive functions were evaluated with Radial Arm Maze Test (RAMT).
Article Synopsis
- - The study explored the effects of cannabinoid systems and nesfatin-1 on sleep, metabolism, and food intake, specifically focusing on 72-hour REM sleep deprivation in mice and the role of specific cannabinoid receptors (CB1R and CB2R).
- - Mice were divided into different groups and received various injections to assess changes in nesfatin-1 levels and insulin resistance, with results indicating that cannabinoid treatment decreased brain nesfatin-1 positivity while blocking receptors prevented this reduction.
- - Findings suggested that increased insulin resistance was linked to CB2 receptor activation, which occurred independently of changes in central nesfatin-1 levels, indicating a complex interaction between these systems.
The medial olivocochlear efferent (MOCE) branch synapses with outer hair cells (OHCs), and the efferent pathway can be activated via a contralateral acoustic stimulus (CAS). The activation of MOCE can change OHC motile responses and convert signals that are capable of controlling the sensitivity of the peripheral hearing system in a frequency-specific manner. The aim of this study was to examine the MOCE system activity in professional musicians using transient evoked otoacoustic emission test and CAS.
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