What is the relationship between the choroidal vascularity ındex (CVI) and myopia?

Purpose: To examine the detailed vascular and morphological characteristics of the choroidal tissue in subjects with myopia.

Methods: A total of 111 subjects with myopia were included in the study. The study was conducted in three groups according to spherical equivalent(SE).

Exercise-induced dynamic mitral regurgitation is associated with outcomes in patients with ischaemic cardiomyopathy.

Aims: Ischaemic mitral regurgitation (MR) is a dynamic condition influenced by global and regional left ventricular remodelling as well as mitral valvular deformation. Exercise testing plays a substantial role in assessing the haemodynamic relevance of MR and is recommended by current guidelines. We aimed to assess the prevalence, haemodynamic consequences, and prognostic impact of dynamic MR using isometric handgrip exercise.

Immune regulation is more effective in the U937 inflammation model with mesenchymal stem cell extracellular vesicles stimulated by pro-inflammatory cytokines.

Mesenchymal stem cells (MSCs), which are multipotent adult cells with many therapeutic effects, can be derived from stromal tissues. MSCs also exert immunoregulatory effects through extracellular vesicles (EVs), cell membrane structures that carry paracrine factors. It is thought that the mediators (cytokines, growth factors, etc.

The Effect of Tamsulosin on Iris Morphology, Ciliary Muscle Thickness, and Pupil Diameter.

Purpose: To investigate the effect of tamsulosin on iris morphology, ciliary muscle thickness (CMT), pupil diameter (PD), and pupil responses to light using anterior segment optical coherence tomography and corneal topography.

Design: Prospective clinical before-and-after study METHODS: The right eyes of 43 patients with newly diagnosed benign prostatic hyperplasia were included in this study. Iris dilator muscle region (DMR) thickness, sphincter muscle region (SMR) thickness, DMR/SMR ratio, PD (scotopic, mesopic and photopic light conditions), CMT1 (1 mm posterior to the scleral spur), CMT2 (2 mm posterior to the scleral spur), CMT3 (3 mm posterior to the scleral spur) and anterior chamber depth (ACD) were measured before and after dilation.

Updates on Breast Reconstruction: Surgical Techniques, Challenges, and Future Directions.

The increasing global incidence of breast cancer underscores the significance of breast reconstruction in enhancing patients' quality of life. Breast reconstruction primarily falls into two categories: implant-based techniques and autologous tissue transfers. In this study, we present a comprehensive review of various aspects of implant-based reconstruction, including different types of implants, surgical techniques, and their respective advantages and disadvantages.

Investigation of integron gene cassettes in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates.

Background: The spread of antibiotic-resistance genes among healthcare-associated infections (HAIs) poses serious problems in the treatment of these infections. Recently, these resistance genes have also been shown to be present in integrons.

Objectives: By focusing on integron-mediated mechanisms of antibiotic resistance, we sought to elucidate the genetic determinants underpinning the development of multidrug resistance in clinical isolates of Acinetobacter baumannii.

The effect of pranic healing based on Rogers' therapeutic touch on cardiorespiratory indices and pain during venipuncture in pediatrics: A randomized clinical trial.

Background: Venipuncture is a commonly performed but distressing procedure for children, often leading to significant pain and anxiety. This study aimed to evaluate the effect of Pranic Healing, based on Rogers' Therapeutic Touch Nursing Theory, on the cardiorespiratory indices and pain associated with venipuncture in children.

Methods: This double-blind, randomized clinical trial was conducted on a cohort of 46 school-aged children, selected via convenience sampling, at a hospital in Northern Cyprus.

AI-Powered Multimodal Modeling of Personalized Hemodynamics in Aortic Stenosis.

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However, their use is currently limited by complex workflows necessitating lengthy expert-driven manual operations.

Eligibility for Transcatheter Tricuspid Valve Interventions in Patients With Tricuspid Regurgitation.

Background: It remains unclear what proportion of patients with tricuspid regurgitation (TR) are suitable candidates for transcatheter tricuspid valve intervention (TTVI) in clinical practice.

Objectives: The aim of this study was to ascertain the prevalence of eligibility for tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) devices among patients with TR.

Methods: The tricuspid valve anatomy of all consecutive patients with TR who were considered for TTVI in local heart team conferences was retrospectively reviewed.

Attitudes toward and exposure to gender discrimination in work life by pulmonologists and thoracic surgeons: a questionnaire-based survey among Turkish thoracic society members.

Background: This study aimed to evaluate attitudes toward and exposure to gender discrimination in work life by chest diseases specialists and thoracic surgeons.

Methods: A total of 275 members of Turkish Thoracic Society (TTS) were included on a voluntary basis in this online cross-sectional questionnaire-survey using an internal member-only social media platform of TTS. The questionnaire form elicited items on sociodemographic characteristics, occupational characteristics and gender discrimination in work life (general opinions, attitudes and exposure).

Growth Dynamic of the Dorsum Sellae in Fetuses.

Objective: To determine the dimension of the dorsum sellae (DS) in fetuses.

Methods: Skull bases of 32 fetuses aged from 17 to 32 weeks were included in the work. The length of the DS at its superior border (DSL-SB) and the thickness of DS at its middle part (DST-ML) were measured.

Sphenoid Ridge in Fetuses: Size Analysis, Classification, and Clinical Implications.

Objective: To identify the size and angle of the sphenoid ridge (SR) in fetuses.

Methods: Skull bases of 32 fetuses (11 males / 21 females) aged 17 to 32 weeks of gestations were included the study. The angle of SR (SRA), length of LW (SRL), and also LW widths at the midline (SRW-ML), at the midpoint (SRW-MP), and at the lateral point (SRW-L) were measured.

Lactoperoxidase Inhibition of Celecoxib Derivatives Containing the Pyrazole Linked-Sulfonamide Moiety: Antioxidant Capacity, Antimicrobial Activity, and Molecular Docking Studies.

Celecoxib derivatives that contain the pyrazole-linked sulfonamide moiety were synthesized, and the in vitro inhibitory impacts of the aforesaid compounds against the lactoperoxidase (LPO) enzyme were researched. To this end, LPO was purified using the affinity chromatography technique with a yield of 12.63% (319.

The Accuracy of Intraoral Scanners in Maxillary Defects with Different Model Variations.

Advances in digital technology and intraoral scanners (IOSs) have the potential to enable accurate digital impressions for patients with maxillary defects. This study aimed to compare the accuracy of IOSs in completely and partially edentulous models with maxillary defects. Three polyurethane models-one completely edentulous (CE) and two partially edentulous, following Aramany classifications I (ACI) and II (ACII)-were created using stereolithography.

The effects of different lighting conditions on the accuracy of intraoral scanning.

Purpose: This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.

Materials And Methods: Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch.

A novel normonoterpene glycoside and a new benzophenone derivative from Hypericum cerastioides and their in vitro cytotoxic activities.

Phytochemical investigations on the aerial parts of Hypericum cerastioides led to the isolation and identification of a novel normonoterpene (1) and a previously undescribed benzophenone glycoside (3) along with eleven known secondary metabolites (2, 4-13). Their structures were deduced based on extensive 1D and 2D NMR analyses as well as HRESIMS. Compound 1 is a rare type of normonoterpene derivative with eight carbon atoms.

The Effect of Super Brain Yoga on Concentration, Memory, and Academic Progress in Nursing Students: A Quasi-Experimental Study.

Background: During university life, students often face significant changes in relationships and academic pressures. Given the stressors faced by nursing students and the importance of their academic success, the study aimed to assess the impact of Super Brain Yoga on nursing students' concentration, memory, and academic progress.

Methods: This quasi-experimental study was conducted on 59 nursing students at Near East University in Cyprus from February to June 2023.

Science-Based Mobile Apps for Reducing Anxiety: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examines the effectiveness of science-based mobile apps for reducing anxiety. A systematic review was employed to identify experimental studies on science-based mobile applications developed anxiety disorders. International databases such as PubMed, Web of Science, SCOPUS and ProQuest were searched to locate relevant articles.

Cardiac MRI in infarct-like myocarditis: transmural extension of late gadolinium enhancement is associated with worse outcomes.

Objectives: To assess the prognostic value of cardiac MRI (CMR) parameters for the occurrence of major adverse cardiac events (MACE) in patients with infarct-like myocarditis.

Methods: In this retrospective single-center study, patients with CMR-confirmed acute myocarditis with infarct-like presentation were identified (2007-2020). Functional and structural parameters were analyzed including late gadolinium enhancement (LGE).

Early integration of palliative care versus standard cardiac care for patients with heart failure (EPCHF): a multicentre, parallel, two-arm, open-label, randomised controlled trial.

Background: Heart failure is a substantial global health concern that severely affects patients' quality of life. We aimed to compare the effects of early integration of palliative care (EIPC) and standard cardiac care on health status and mood of patients with non-terminal heart failure.

Methods: EPCHF was a multicentre, parallel, two-arm, open-label, randomised controlled trial carried out at University Hospital Bonn and University Hospital Düsseldorf in Germany.

Crista Galli Morphology in Fetuses.

Objective: To determine alterations in the crista galli (CG) size in fetuses with advancing weeks.

Methods: Skull bases of 32 fetuses (11 males/21 females) aged 17 to 32 weeks in utero were included in the study. The width (width of CG), height (height of CG), and length (length of CG) of CG were measured, and also olfactory fossa depth (OFD) was measured to determine the relation of CG with OFD.