Evaluation of the effect of methylphenidate by computed tomography, electroencephalography, neuropsychological tests, and clinical symptoms in children with attention-deficit/hyperactivity disorder: A prospective cohort study.

Background: Stimulant drugs are the most commonly used treatments for attention-deficit/hyperactivity disorder (ADHD), although the mechanism of action of these drugs is still not entirely understood.

Objective: The aim of this study was to investigate the effects of the psychostimulant drug methylphenidate (MPH) on regional cerebral blood flow (rCBF), electrical activity of the brain, and clinical symptoms in children with ADHD using single-photon emission computed tomography (SPECT), electroencephalography (EEG), and neuropsychological tests.

Methods: In this prospective cohort study, pediatric outpatients received MPH for 3 months at a mean dose of 1 mg/kg · d (range, 0.

[The reliability and validity of the children's negative cognitive errors questionnaire].

Objective: The Children's Negative Cognitive Errors Questionnaire (CNCEQ) is a self-report scale measuring negative cognitive errors in children. The aim of this study was to examine its reliability and validity, and to obtain its norms for Turkish children.

Method: The study was carried out at 3 public schools representing 3 different socioeconomic statuses.

[The symptoms of PTSD, depression and anxiety in adolescent students three and a half years after the Marmara earthquake].

Objective: To screen the symptoms of posttraumatic stress disorder (PTSD), depression and anxiety in adolescent students three and a half years after the Marmara earthquake in Turkey.

Method: Overall 334 students were selected from secondary schools located within Kocaeli province in Turkey, three and a half year after a severe earthquake. They were chosen to participate in this cross-sectional study by simple random sampling.