Publications by authors named "Ozlem Ercal"
Article Synopsis
- The study investigates corneal healing responses in mice after various chemical and mechanical injuries, which is crucial for understanding how such injuries affect the cornea and the effectiveness of treatments.
- Four groups of mice underwent injuries using methods like AlgerBrush, NaOH, and ethanol, with their recovery assessed using slit-lamp examinations and optical coherence tomography over 14 days.
- Results indicated that chemical injuries led to less corneal opacity and better epithelial thickness compared to mechanical injuries, suggesting inflammation significantly impacts healing outcomes.
The cornea is critical for vision, and corneal healing after trauma is fundamental in maintaining its transparency and function. Through the study of corneal injury models, researchers aim to enhance their understanding of how the cornea heals and develop strategies to prevent and manage corneal opacities. Chemical injury is one of the most popular injury models that has extensively been studied on mice.
View Article and Find Full Text PDFExtracellular matrix (ECM) stiffness is correlated to malignancy and invasiveness of cancer cells. Although the mechanism of change is unclear, mechanical signals from the ECM may affect physical properties of cells such as their density profile. The current methods, such as Percoll density-gradient centrifugation, are unable to detect minute density differences.
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