Determination of the Relationship Between Craving and 4-repeat Allele of Gene Polymorphism in the Early Withdrawal Period of Alcohol Use Disorders.

Objective: Alcohol use disorder (AUD) is a disease with chronic relapses. Risk factors of craving, which is thought to be one of the predictors of relapse, have been studied for a long time. The gene is located on chromosome 11p and has a 48-base pair variable number of tandem repeat (VNTR) polymorphisms in the 3rd exon.

Predictors of Alcohol Use Disorder: MAOA Gene VNTR Polymorphism, Impulsivity, and Personality Traits.

Objective: Risk factors for alcohol use disorder have been investigated for a long time. The MAOA gene presents several polymorphisms, including 30-bp variable number tandem repeat sequences (VNTR) in the promoter region. In this study, temperament characteristics, impulsivity, and frequency of MAOA-u VNTR polymorphism were investigated as risk factors for alcohol use disorder.