Undescribed and known phenolic acid derivatives with significant antioxidant activity from the Scorzonera parviflora Jacq. roots.

The antioxidant activity of Scorzonera parviflora Jacq. roots were assessed by measuring their ability to scavenge ABTS and DPPH radicals. Bioactivity-guided fractionation was utilized to identify the compound(s) responsible for this activity.

Chemical compounds isolated from aerial parts of , a new species from Türkiye.

identified in 2019 for the first time is an endemic species of genus belonging to Caryophyllaceae family. Ten compounds were isolated from aerial parts of the plant. The potential antioxidant and anti-inflammatory effects of all four phases (hexane, chloroform, ethyl acetate, and water) from the methanol extract of the plant were investigated.

Immunomodulatory and anti-inflammatory therapeutic potential of gingerols and their nanoformulations.

Ginger ( Roscoe), a member of the Zingiberaceae family, is one of the most popular spices worldwide, known since ancient times, and used both as a spice and a medicinal plant. The phenolic compounds found in ginger are predominantly gingerols, shogaols, and paradols. Gingerols are the major phenolic compounds found in fresh ginger and contain mainly 6-gingerol as well as 4-, 5-, 8-, 10-, and 12-gingerols.

Assessment of Correlation Analysis, Phytochemical Profile, and Biological Activities of Endemic Scorzonera Species from Turkey.

Scorzonera species belong to the Asteraceae family comprising more than 25000 species. The present study aimed to examine the phytochemical profiles and biological activities of S. sandrasica Hartvig et Strid, S.

Advances in Understanding the Role of Aloe Emodin and Targeted Drug Delivery Systems in Cancer.

Cancer is one of the important causes of death worldwide. Despite remarkable improvements in cancer research in the past few decades, several cancer patients still cannot be cured owing to the development of drug resistance. Natural sources might have prominence as potential drug candidates.

A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease.

Parkinson's Disease (PD) is a multifaceted disorder with various factors suggested to play a synergistic pathophysiological role, such as oxidative stress, autophagy, pro-inflammatory events, and neurotransmitter abnormalities. While it is crucial to discover new treatments in addition to preventing PD, recent studies have focused on determining whether nutraceuticals will exert neuroprotective actions and pharmacological functions in PD. Quercetin, a flavonol-type flavonoid, is found in many fruits and vegetables and is recognised as a complementary therapy for PD.

Isolation and Identification of F Lavonol Glycosides from (Boiss. & Huet).

In the last five decades study on plant secondary metabolites have been increasing. Higher plants with a wide range of secondary metabolites have been very important in the search of new therapeutic agents. In this study secondary metabolites of (Boiss.

Evaluation of the Antidiabetic Activity of Rothm. in Mice with Diabetes Induced by Alloxan.

Objectives: species are used in Turkish folk medicine for the treatment of many diseases together with diabetes. , belonging to this genus, is widely distributed in Eastern Anatolia as well as in Caucasia, northern and northeastern Iran, and northern Iraq.

Materials And Methods: Methanolic-water extracts of the aerial parts and roots of were evaluated for their hypoglycemic activities in mice with alloxan-induced diabetes in order to verify its usage in folk medicine.

Antimicrobial and Anti-Inflammatory Activity of Some L. (Fabaceae) Species Growing in Turkey.

Objectives: The present study aimed to evaluate the antimicrobial and anti-inflammatory activities of methanol extracts and n-hexane, ethyl acetate, chloroform, and water fractions of five species, namely subsp. , and , growing in Turkey.

Materials And Methods: The antimicrobial activities were screened against ATCC 29213, ATCC 6633, ATCC 25922, ATCC 27853, and ATCC 10231.

Inhibitory activity of Podospermum canum and its active components on collagenase, elastase and hyaluronidase enzymes.

Present study is aimed to investigate in vitro inhibitory effects of the extract prepared from the aerial parts of Podospermum canum (syn: Scorzonera cana var. jacquiniana) (Asteraceae) on hyaluronidase, collagenase, and elastase enzymes using a bioassay-guided fractionation. Inhibitory effects of the extract, sub-extracts, fractions obtained by column chromatography, and isolated compounds on collagenase, elastase, and hyaluronidase were performed by using in vitro enzyme inhibitory assays based on spectrophotometric evaluation.

Inhibitory activity of Scorzonera latifolia and its components on enzymes connected with healing process.

Ethnopharmacological Relevance: Scorzonera latifolia (Fisch. & Mey.) DC.

Quantification of Galantamine in Species by High Performance Liquid Chromatography.

Objectives: This study describes the qualitative and quantitative analysis of galantamine in species growing in Turkey.

Materials And Methods: Galantamine was isolated from bulbs and the structure of the compound elucidated by spectroscopic methods. The qualitative and quantitative analysis of galantamine was investigated in subsp.

Phytochemical Analysis of and -Hexane Extracts and the HPLC Quantitation of Triterpenes.

Previously tested -hexane extracts of the showed promising bioactivity in vivo. Because triterpenes could account for this activity, -hexane extracts were analyzed by HPLC to identify and quantify the triterpenes as the most abundant constituents. Other and species, potentially containing triterpenic aglycones, were included in the study.

In vivo wound-healing activity of Euphorbia characias subsp. wulfenii: Isolation and quantification of quercetin glycosides as bioactive compounds.

Ethnopharmacological Relevance: The latex and the aerial parts of Euphorbia characias L. (Euphorbiaceae) have been used as medicinal plant to treat wounds and warts in traditional medicine.

Aim Of The Study: The effect of the plant extract was tested in vivo and in vitro with experimental models to find scientific evidence for traditional use in wound healing.

activity assessment of some species used as traditional wound healer along with identification of the phytochemical profile by a new validated HPLC method.

Objectives: species are traditionally used as insecticide, and externally wound healer as well as for anti-inflammatory and antihistaminic properties. The wound-healing and anti-inflammatory potential of four species, (Lam.) Willd.

Isoflavonoids as wound healing agents from Ononidis Radix.

Ethnopharmacological Relevance: Dried roots of Ononis spinosa L. are traditionally used for their diuretic, anti-inflammatory and wound healing effects.

Aim Of The Study: Isolation of the bioactive compounds of Ononis spinosa L.

Evaluation of Antioxidant Activities and Phenolic Compounds of (Fisch. & Mey.) DC. Collected from Different Geographic Origins in Turkey.

Objectives: The chemical composition of plants is considered to be affected by many parameters. Therefore, the region where the samples are collected is likely to have an influence on the composition of phenolic compounds, so that their biological activities. In the present study, evaluation of antioxidant activity potentials of (Fisch.

Wound healing and anti-inflammatory activity of some Ononis taxons.

Ononis species are used for their laxative, diuretic, analgesic, anti-inflammatory, antiviral, cytotoxic and antifungal effects as well as against skin diseases for wound healing activity. In the light of this information n-hexane, ethylacetate and methanol extracts prepared from Ononis spinosa L. subsp.

Evaluation of hepatoprotective and antidiabetic activity of Alchemilla mollis.

Alchemilla mollis (Buser) Rothm aerial part and root methanolic-water extracts were evaluated for their hepatoprotective activity on carbon tetrachloride induced hepatotoxicity and hypoglycemic activity on alloxan-induced diabetic mice. None of the tested extracts exhibited effects on blood glucose levels. However hepatoprotective activity results have revealed that serum ALT levels were significantly lowered by both the aerial part and root extracts at doses of 100mg/kg and 200mg/kg.

Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-κB Activation, Showing Anti-Inflammatory Effect in Vitro.

Scorzonera species are used in different folk medicines to combat many diseases, including the illnesses connected with inflammation. Previous experiments showed anti-inflammatory activity of Scorzonera extracts in vivo. S.

Phytochemical analyses and effects of Alchemilla mollis (Buser) Rothm. and Alchemilla persica Rothm. in rat endometriosis model.

Purpose: The aim of the present study is to evaluate the treatment potential of Alchemilla mollis (Buser) Rothm. and Alchemilla persica Rothm. in the experimentally induced endometriosis model in rats.

Prospective neurobiological effects of the aerial and root extracts and some pure compounds of randomly selected Scorzonera species.

Context: Scorzonera L. species (Asteraceae) are edible and as medicinal plants are used for various purposed in folk medicine.

Objective: The methanol extracts of the aerial parts and roots from 27 Scorzonera taxa were investigated for their possible neurobiological effects.

In vivo and in vitro evaluation of the therapeutic potential of some Turkish Scorzonera species as wound healing agent.

Wound healing and anti-inflammatory effects of aerial parts and roots of S. acuminata, S. cana var.

Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects.

Ethnopharmacological Relevance: Scorzonera species are mainly used against inflammation and to relieve pain in Turkish traditional medicine. Therefore, we aimed to assess in vivo anti-inflammatory and antinociceptive activities of the aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina, Scorzonera cana var.

A new triterpene from Scorzonera latifolia (Fisch. and Mey.) DC.

A novel triterpene 1 (3-β-hydroxy-fern-7-en-6-one-acetate) together with four known compounds, urs-12-en-11-one-3-acetyl (2), 3-β-hydroxy-fern-8-en-7-one-acetate (3), olean-12-en-11-one-3-acetyl (4) and leucodin (5) were obtained from the S. latifolia roots. All compounds were isolated from the n-hexane extract of S.