Estimating time-to-total knee replacement on radiographs and MRI: a multimodal approach using self-supervised deep learning.

Purpose: Accurately predicting the expected duration of time until total knee replacement (time-to-TKR) is crucial for patient management and health care planning. Predicting when surgery may be needed, especially within shorter windows like 3 years, allows clinicians to plan timely interventions and health care systems to allocate resources more effectively. Existing models lack the precision for such time-based predictions.

Standardised Pressure Injury Prevention Protocol (SPIPP- Adult) Checklist 2.0: Language and Content Validity Study.

Introduction: Implementation of clinical practice guidelines, an important strategy in the prevention of pressure injuries, enables the nurse to interpret evidence-based guideline recommendations, reduce errors, ensure compliance and standardisation of complex processes, manage patient-related risks and systematically regulate all preventable conditions.

Objective: This study was conducted to ensure the Turkish language and content validity of the Standardised Pressure Injury Prevention Protocol (SPIPP- Adult) Checklist 2.0.

Artificial intelligence in knee osteoarthritis: A comprehensive review for 2022.

Objective: The aim of this literature review is to yield a comprehensive and exhaustive overview of the existing evidence and up-to-date applications of artificial intelligence for knee osteoarthritis.

Methods: A literature review was performed by using PubMed, Google Scholar, and IEEE databases for articles published in peer-reviewed journals in 2022. The articles focusing on the use of artificial intelligence in diagnosis and prognosis of knee osteoarthritis and accelerating the image acquisition were selected.

Effectiveness of a hybrid approach in integrating GLP-1 agonists and lifestyle guidance for obesity and pre-diabetes management: RWE retrospective study.

Aim: Emerging anti-obesity pharmacotherapy provides an option to correct maladaptive physiological and hormonal changes associated with obesity. One of the widely used medications in this context is glucagon-like peptide 1 (GLP-1) agonists. However, the misuse of these medications without any guidance and monitoring of lifestyle modifications can lead to unfavorable outcomes.

Effectiveness of a hybrid technology enabled care model as measured by ICHOM standard set on established and managed type 2 diabetes already using medications: A RWE retrospective study.

Aims: Diabetes is a pressing global health issue, demanding innovative strategies for improved treatment. However, traditional care often falls short of patient goals. To address this, digital health solutions, including smartphone apps and remote monitoring, have emerged as crucial in diabetes management.

Comparison of the effects of face-to-face and electronic peer mentoring on students' care plan preparation and motivation levels.

Background: It is a basic requirement in professional nursing education that nursing students learn the process of caring as the entity at the center of nursing practice. Peer mentoring programs can be beneficial for the mutual growth of mentors and mentees and improve the care competencies of nursing students.

Objective: To compare the effects of face-to-face and electronic peer mentoring on students' nursing process-based patient care plan preparation and motivation levels for the course.

Synthesis and Application of Reactive Acrylic Latexes: Effect of Particle Morphology.

The aim of the study is the synthesis and characterization of epoxy functional reactive polyacrylic latexes, e.g., poly (BA-co-MMA-co-AN-co-GMA) with core/shell and non-structured (random) particle morphologies.

Nursing students' classroom climate perceptions: A longitudinal study.

Background: As a versatile and dynamic process, classroom climate directly affects the learning levels of students and their quality of life while in school.

Objectives: The study was conducted to explore and compare nursing students' perceptions of classroom climate throughout four years of university education and to evaluate the influencing factors.

Design And Settings: The longitudinal study was conducted between 2017 and 2020 in the nursing department of a university in Turkey.

Determination of perception levels of student nurses about nursing diagnosis.

Objective: To determine perception levels of student nurses about nursing diagnosis.

Methods: The descriptive, comparative, cross-sectional study was conducted at the Nursing Department, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Turkey, in December 2015, and comprised nursing students studying in the 2nd, 3rd and 4th grades. Data was collected using a personal information form and the Perceptions of Nursing Diagnosis Survey.

The impacts of wave energy conversion on coastal morphodynamics.

In recent decades, utilization of renewable energy resources, including ocean waves, has been promoted as part of a global effort to transition away from the use of fossil fuels. This is largely due to the accompanying greenhouse gas emissions and its catastrophic impacts on the environment, which are expected to worsen with the changing climate. Energy from ocean waves can be harnessed and converted into electricity with devices referred to as wave energy converters (WECs).

46 XX male syndrome with hypogonadotropic hypogonadism: A case report.

We report a 46 XX male syndrome diagnosed after failure of gonadotropin therapy taken for hypogonadotropic hypogonadism due to a pituitary macroadenoma. A 39-year-old man with a non-functioning pituitary macroadenoma was admitted to our clinic due to vision loss and infertility. After pituitary surgery, vision loss improved while infertility still existed.

Serum activities of dipeptidyl peptidase-4 and adenosine deaminase in polycystic ovary syndrome: association with obesity.

Dipeptidyl peptidase-4 (DPP-4) plays a role in metabolic and inflammatory diseases. Increased adenosine deaminase (ADA) has been suggested to induce insulin resistance and inflammation. We measured serum DPP-4 and ADA activities.

Performance analysis of different classification algorithms using different feature selection methods on Parkinson's disease detection.

Background: In diagnosis of neurodegenerative diseases, the three-dimensional magnetic resonance imaging (3D-MRI) has been heavily researched. Parkinson's disease (PD) is one of the most common neurodegenerative disorders.

New Method: The performances of five different classification approaches using five different attribute rankings each followed with an adaptive Fisher stopping criteria feature selection (FS) method are evaluated.

Effects of different covariates and contrasts on classification of Parkinson's disease using structural MRI.

Three-dimensional magnetic resonance imaging (3D-MRI) has been effectively used in the diagnosis of progressive neurodegenerative diseases including Parkinson's disease (PD). Pre-processing of 3D-MRI scans plays an important role for post-processing. In this paper, voxel-based morphometry (VBM) technique is used to compare morphological dierences of PDs versus healthy controls (HCs) in gray matter (GM) and white matter (WM).

Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto's thyroiditis?

Recent studies imply that euthyroid Hashimoto's thyroiditis (HT) might be related with impaired HRQoL, depression and anxiety. Ninety three patients with euthyroid HT and 31 age- and gender-matched euthyroid control subjects were enrolled into this study. SF-36 questionnaire, Beck Depression Inventory and Beck Anxiety Inventory tests were used for evaluating HRQoL, depression and anxiety.

A Case Report of Bilateral Adrenal Sarcomatoid Carcinoma.

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Sarcomatoid adrenal carcinoma is even more aggressive type of ACC. Bilateral malignant adrenal tumors are extremely rare except for those that represent metastasis from an extra-adrenal organ.

Cephalometric assessment of soft tissue morphology of patients with acromegaly.

Aim: To assess the sagittal soft tissue morphology of patients with acromegaly in comparison with a healthy control group.

Methods: Twenty-seven patients with acromegaly (11 male, 16 female; mean age 47.3 ± 11.

ASYMMETRIC DIMETHYLARGININE LEVELS AND ATHEROSCLEROSIS MARKERS IN CUSHING SYNDROME.

Objective: As a consequence of hypercortisolism, Cushing syndrome (CS) is frequently observed with other diseases that are associated with atherosclerosis, including diabetes mellitus, dyslipidemia, hypertension, and obesity. Cardiovascular disease (CVD) is the primary cause of mortality and morbidity in CS. We investigate CVD risk markers such as asymmetric dimethylarginine (ADMA), lipoprotein-associated phospholipase A2 (Lp-PLA2), highsensitive C-reactive protein (hsCRP), homocysteine, lipid levels, ankle-brachial index (ABI), and carotid intimamedia thickness (CIMT) in CS.

Lymph node fine-needle aspiration washout thyroglobulin in papillary thyroid cancer: Diagnostic value and the effect of thyroglobulin antibodies.

Purpose: Thyroglobulin (Tg) assessment in the needle washout after fine-needle aspiration biopsy (FNAB) of a suspicious neck lymph node (LN) is known to improve the diagnostic accuracy in patients with papillary thyroid cancer (PTC). However, there is still controversy on the best diagnostic cut-off levels for FNAB-Tg and whether thyroglobulin antibody (TgAb) positivity affects FNAB-Tg. The objectives of this study were to determine (i) the diagnostic power of different cut-offs for FNAB-Tg and (ii) if serum TgAb(+) negatively affects the FNAB-Tg evaluation.

Vitamin D-binding protein and free vitamin D concentrations in acromegaly.

Free 25-hydroxyvitamin D [25(OH)D] is suggested to be important in the determination of vitamin D deficiency, since vitamin D-binding protein (VDBP) may affect total 25(OH)D levels. There are no data about free 25(OH)D concentrations in acromegaly. We aimed to investigate serum VDBP and total and free 25(OH)D levels in patients with acromegaly in comparison with control subjects.

Selenoprotein P is not elevated in gestational diabetes mellitus.

Selenoprotein P concentrations have been found to be associated with insulin resistance and elevated in patients with type 2 diabetes mellitus (DM). The aim of the present study was to investigate circulating selenoprotein P level and its possible relationship with metabolic parameters in gestational diabetes mellitus (GDM). Plasma selenoprotein P concentrations were measured in 30 pregnant women with GDM, 35 pregnant women without GDM and 22 healthy nonpregnant women.

Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index in patients with differentiated thyroid cancer.

The cardiovascular effects of short-term overt hypothyroidism are not well known. We investigated proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and the ankle brachial index (ABI) in thyroid cancer patients with short-term overt hypothyroidism due to thyroid hormone withdrawal (THW). Twenty-one patients requiring radioactive iodine (RAI) ablation or scanning and 36 healthy control subjects were enrolled.

The Assessment of Atrial Electromechanical Delay in Patients With Acromegaly.

Background: We aimed to evaluate whether atrial electromechanical delay (AEMD) measured by tissue Doppler imaging (TDI), which is an indicator for structural and electrical remodelling of the atria, is prolonged in patients with active or inactive acromegaly, or both, compared with a control group.

Methods: A total of 34 patients with acromegaly (18 active/16 inactive) and 35 patients as a control group were enrolled. Both intra- and inter-AEMD were calculated by TDI.

Craniofacial and pharyngeal airway morphology in patients with acromegaly.

Objective: The aim of this study was to assess differences in craniofacial characteristics, upper spine and pharyngeal airway morphology in patients with acromegaly compared with healthy individuals.

Materials And Methods: Twenty-one patients with acromegaly were compared with 22 controls by linear and angular measurements on cephalograms. The differences between the mean values of cephalometric parameters were analyzed with Mann-Whitney U-test.