Publications by authors named "Ozhiganov E"

The authors studied the results of repeated radical operations performed in 73 patients who had been subjected earlier to exploratory and palliative operations. During repeated interventions radical operations were conducted on 54 (74%) patients which were of a combined character in 11 (20.4%) of them.

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The levels of tumor markers were determined in 173 patients with rectal cancer recurrences by radioimmunoassay. An increase in a CEA level was observed most frequently (92.5%).

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Of 153 patients with confirmed rectal cancer CEA was recorded in 139 (90.8%); erroneous results were noted in 14 (9.2%) patients; in scintigraphy with 67Ga-citrate and 111In-bleomycin diagnoses coincided in 147 (96.

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The carcinoembryonic antigen content (CEA) was studied in 163 patients who had been subjected to surgical treatment. The content of antigen in blood plasma was determined by the radioassay. It is shown that a high pre- and postoperative CEA level may be indicative of the spread of the neoplastic process, nonradical character of the treatment, and an unfavourable prognosis.

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Scintigraphy with 67Ga-citrate and 111In-bleomycin was performed in 26 patients with primary rectal cancer, 176 patients with suspected recurrent tumors, and in 34 patients without clinicoroentgenological signs of cancer recurrence. A focus of higher accumulation of these radionuclides in the rectal area was recorded in all 26 patients. Of 176 patients with symptoms of recurrence tumors were detected by means of ultrasonic and computed tomography of the small pelvis in 158 patients.

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Results of reoperations for recurrent cancer of the large bowel in 164 patients are analyzed. Radical operations were performed in 110 patients (67.0%).

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A definition of rectal cancer recurrence and a relevant classification are given on the basis of the literature data and the authors' findings, thus providing a means for comparing treatment results and establishing rational procedures of rectal cancer recurrence therapy.

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A study was made of the results of measuring the carcinoembryonic and carbohydrate antigens using a kit of reagents in 75 patients with rectal cancer recurrences and metastases. The concentration of these antigens in healthy persons was for CEA 6.4 +/- 0.

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The paper is concerned with an analysis of transverse slices of male and female small pelvis in CT-images. A high CT resolution in the characteristics of topical interrelationships of the pelvic organs was shown. A variability of the interrelationships of the pelvic organs with respect to their condition and the value of this factor for correct interpretation of tomograms were shown.

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The paper is concerned with the results of the determination of beta 2-microglobulin (beta 2-MG) and CEA concentrations in rectal cancer patients to improve diagnosis of recurrences. The CEA content was shown to be the most specific indicator reflecting the course of a recurring tumor process whereas the beta 2-MG test was found inappropriate for the purpose though it might be used in suspected involvement of the urinary organs in a tumor process.

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The results of thermography and computed tomography of 168 patients following rectum extirpation for cancer were analysed. Of them 116 had symptoms of cancer recurrence and 52 with a poor prognosis were without signs of recurrence. In the 1st group thermography made it possible to record recurrences in 106 (91.

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A treatment modality employing radiotherapy with subsequent hyperglycemia induction was evolved in experiments on mice and then clinically tested in 32 cases of inoperable locally--extensive primary and recurrent cancer of the rectum. A 50% regression of tumor was registered in 14 (43.0%) out of 32 patients treated with radiotherapy in combination with hyperglycemia.

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The paper is concerned with the results of ultrasonic tomography carried out in 487 radically-operated cases of rectal cancer. Tumor was detected in 103 out of 136 patients with clinically manifest recurrence (76.9%) (group 1).

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