Nucleosome assembly protein 1-like 1 (NAP1L1) in gastric cancer patients: a potential biomarker with diagnostic and prognostic utility.

Background: The nucleosome assembly protein 1-like 1 (NAP1L1) is suggested to have an oncogenic role in several tumors based on its overexpression. However, its diagnostic and prognostic role in gastric cancer remains unclarified. This study aimed to evaluate the diagnostic and prognostic utility of NAP1L1 in gastric cancer patients.

B7-H3: A Useful Emerging Diagnostic Marker for Colon Cancer.

Background: Colon cancer is the second most common malignancy causing the majority of cancer-related deaths. B7-H3 concentrations have drawn major interest as possible diagnostic biomarkers of cancer. The aim of this study was to measure the preoperative serum B7-H3 levels and to determine those that are replaced in colon cancer.

The Utility of Serum Vasorin Levels as a Novel Potential Biomarker for Early Detection of Colon Cancer.

Objective The objective of this study was to investigate the utility of vasorin, a newly discovered transmembrane protein, as a novel biomarker in the early detection of colon cancer. Methods A total of 80 patients aged 55-70 years, diagnosed with colon cancer and followed up in our clinics, and 50 healthy volunteer blood donors were included in the study. Participants' demographics such as age, gender, and vasorin levels were recorded and compared between the patient and control groups.

Nidogen-2: A new biomarker in colon cancer patients.

Aim: In the present study, we followed Nidogen-2 levels and clinicopathological parameters of patients with colon cancer.

Material And Methods: Eighty-eight patients (F/M, 43/45; Mean age ± SD, 57.86 ± 1.

Evaluation of preoperative and postoperative total serum sialic acid levels in patients with colon cancer.

Aim: The aim of this study was to compare the preoperative and postoperative (48th hour) total serum sialic acid levels of the patients with colon cancer and to investigate if the total serum sialic acid levels can be used as a tumor marker in colon cancer.

Methods: Preoperative and postoperative (48th hour) total serum sialic acid levels of 100 patients that were diagnosed with colon cancer and 70 healthy individuals were examined. All total serum sialic acid levels were determined by the methods of Warren.

A novel approach for preventing recurrence of malign pleural effusion: early phase pleurodesis.

Introduction: The effective control of malignant pleural effusion (MPE) is of paramount importance in the treatment of patients with disseminated cancer. In this study, we compared two different approaches (early pleurodesis versus late pleurodesis) to MPE.

Material And Methods: Patients (188 cases) whose primary tumor type was known and who were confirmed to have MPE, were included in the study and were separated into two groups.

Oesophageal foreign bodies caused by meat consumed during the Sacrifice Feast: Our single-centre experience.

Objective: To compare the frequency of oesophageal foreign bodies during the month of Eid-ul-Adha with other months.

Methods: This retrospective study was conducted at YüzüncüYil University Hospital, Van, Turkey, during 2012-16, and comprised individuals who were treated for bone and/or meat fragments lodged in the oesophagus. The number of hospital admissions with diagnosis of oesophageal foreign bodies during Eid-ul-Adha episodes were extricated and compares with similar date for the other months.

Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients.

Objective: Elevated serum Mac 2-binding protein (M2BP) levels have been observed in some cancers. As far as we know, its importance has not been investigated in esophageal squamous cell carcinoma (ESCC). The investigated problem of this study was to evaluate whether there was a difference between ESCC patients and the control group in terms of M2BP.

Serum vascular endothelial growth factor receptor-3 levels in patients with esophageal squamous cell cancer.

Aim: Esophageal cancer is one of the most aggressive tumors of the gastrointestinal tract. In this study, we quantified the serum vascular endothelial growth factor-3 (VEGFR-3) expression in patients with esophageal squamous cell carcinoma (ESCC) to evaluate the role of VEGFR-3 in ESCC.

Materials And Methods: Ninety five patients with ESCC were studied.

Evaluation of the open and laparoscopic appendectomy operations with respect to their effect on serum IL-6 levels.

Background: Postoperative serum inflammatory cytokine levels are thought to reflect the magnitude of surgical stress. Cytokine interleukin-6 (IL-6) is an early marker of systemic inflammatory response and tissue damage. This study evaluated levels of IL-6 after open and laparoscopic appendectomy to compare the degree of surgical stress associated with these procedures.

Effects of mesenchymal stem cells and VEGF on liver regeneration following major resection.

Purpose: The study aims to determine the effects of mesenchymal stem cell (MSC) therapy and a combination therapy of MSCs transfected with vascular endothelial growth factor (VEGF) for liver regeneration after major resection.

Methods: Thirty-eight rats were divided into four groups: group 1: control (sham operation); group 2: control (70 % hepatic resection); group 3: 70 % hepatic resection + systemically transplanted MSCs; and group 4: 70 % hepatic resection + systemically transplanted MSCs transfected with the VEGF gene. MSCs were injected via the portal vein route in study groups 3 and 4.

Serum leptin levels in gastric cancer patients and the relationship with insulin resistance.

Introduction: Serum leptin levels have been examined in various cancers, with conflicting results. However, there is limited information regarding serum leptin levels and insulin resistance in gastric cancer patients. Therefore, we aimed to investigate serum leptin levels, performance status, insulin levels and insulin resistance in patients with gastric cancer.

The prevalence of helicobacter pylori among dyspeptic patients in an earthquake-stricken area.

Objectives: Helicobacter pylori is a gram-negative, spiral-shaped, urease-producing bacterium with multiple unipolar flagella. Humans are a major reservoir for H. pylori; however, there are no data on the prevalence of H.

Preoperative serum levels of mesothelin in patients with colon cancer.

Background: Screening for biochemical markers is important for diagnosing colon cancer. In this study, the reliability of serum mesothelin levels as a potential diagnostic and screening instrument was evaluated concerning colon cancer.

Methods: Ninety-five patients who had undergone colonoscopic examination and who were diagnosed with colon cancer were included in the study.

Complications following endoscopic retrograde cholangiopancreatography: minimal invasive surgical recommendations.

Background: ERCP has a complication rate ranging between 4% and 16% such as post-ERCP pancreatitis, hemorrhage, cholangitis and perforation. Perforation rate was reported as 0.08% to 1% and mortality rate up to 1.

The preliminary experience in the emergency department of a newly opened penitentiary institution hospital in Turkey.

Background: Emergency cases become a widespread problem in prisons across Turkey. The opening of a new prison hospital in January 2012 within the catchment of Silivri Penitentiary Institution gave a unique opportunity to treat the inmates quickly.

Aims: The study was to conduct an extensive review for documentation of prisoners' healthcare problems leading to emergency admission following the first year after the opening of Penitentiary Institution Hospital and point to decrease redundant hospital transfers of this individual cohort.

Massive Alimentary Tract Bleeding due to Cytomegalovirus Infection in an Elderly Patient.

In recent years, cytomegalovirus (CMV) has been recognized as an important common pathogen in immunocompromized patients. This is due to the increasing number of immunosuppressive medications, intensive cancer chemotherapy use, recurrent transplantations, progressively aging population, and the higher number of human immunodeficiency virus infections. Cytomegalovirus infection especially interests the gastrointestinal tract, anywhere, from the mouth to the anus.

Cutaneous necrosis as a result of isosulphane blue injection in mammarian sentinel lymph node mapping: report of two cases.

Skin-sparing mastectomy with sentinel lymph node biopsy (SLNB) and synchronous breast reconstruction are widely used in breast cancer surgery nowadays. Difficulties in feeling confident in this technique and postoperative surgical complications are the major obstacles against the widespread usage of this technique. Compared with the other surgical techniques, the complications are hard to treat.

Laparoscopic treatment of gallstone ileus.

Gallstone ileus is a rare complication of cholelithiasis that has high morbidity and mortality. An intestinal obstruction can be caused by migration of a large gallstone through a biliary enteric fistula or by impaction within the intestinal tract. In this study, we present the case of an 81-year-old woman with a mechanical bowel obstruction by a gallstone that was treated by laparoscopy.

The effects of aging on lymphocyte subgroups in males and females.

Background: Age-associated immune senescence is a catch-all phrase that has been used to describe a plethora of changes to the immune system across the lifespan. Aging is associated with a decline in immune function. Our aim in this study was to investigate how lymphocyte subgroups in peripheral blood are affected by aging among males and females.

The use of ERCP during pregnancy: is it safe and effective?

Cholangitis and pancreatitis are the most gruesome complications that can be potentially fatal for the mother and fetus. The management of bile stone disease complicated with duct stones during pregnancy is challenging. Conservative treatment instead of surgery has always been advocated due to the increased risk for fetal compromise.

Obese Patients After Laparoscopic Adjustable Gastric Banding Complications and The Influence on Body Mass Index and Comorbidities.

Background/aims: The aim of this study is to present the advantages of LAGB (Laparoscopic adjustable gastric banding), its effects on weight loss and influence on comorbidities such as diabetes and hypertension.

Methodology: 90 middle-aged obese patients with body mass index [BMI] of 35-50 kg/m2 underwent LAGB between October 2007 and April 2010.

Results: There were 33 men and 57 women underwent LAGB.

Desmoid tumor in puerperium period: a case report.

Desmoid tumors (DTs) are rare tumors classified as deep fibromatoses taking origin from fascial or musculoaponeurotic structures. With pregnancy and surgical scars considered in the etiology, most anterior abdominal wall DTs occur in women in their reproductive years, especially during a pregnancy or post-partum. Herein, we present development of DT in a female patient in the post-partum period following cesarean delivery, which manifested itself with a growing mass in anterior abdominal wall.

Is combined therapy more effective than growth hormone or hyperbaric oxygen alone in the healing of left ischemic and non-ischemic colonic anastomoses?

Objective: Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal and ischemic colonic anastomoses in rats.

Methods: Eighty male Wistar rats were divided into eight groups (n = 10). In the first four groups, non-ischemic colonic anastomosis was performed, whereas in the remaining four groups, ischemic colonic anastomosis was performed.