Publications by authors named "Ozgur Batum"

Background: Malignant pleural effusion (MPE) is a condition, that can be seen in 15% of patients diagnosed with cancer. Because of the short overall survival, it is important to identify the appropriate treatment. In addition to the palliation of secondary symptoms due to MPE, it should also be decided in which cases a more aggressive treatment is to be followed.

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Background: The COVID-19 pandemic, which first appeared in Wuhan, China, in December 2019 and spread rapidly around the globe, continues to be a serious threat today. Rapid and accurate diagnostic methods are needed to identify, isolate and treat patients as soon as possible because of the rapid contagion of COVID-19. In the present study, the relation of the semi-quantitative scoring method with computed tomography in the diagnosis of COVID-19 in determining the severity of the disease with clinical and laboratory parameters and survival of the patients were investigated along with its value in prognostic prediction.

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Purpose: The aim of this study was to investigate the correlation of preoperative 18F-fluorodeoxyglucose PET/computed tomography maximum standardized uptake value (SUVmax) in operated non-small cell lung cancer (NSCLC) cases with other prognostic parameters and survival.

Patients And Methods: NSCLC patients treated by surgical resection were imaged with PET within 60 days before surgery.

Results: Overall, 525 cases consecutive patients were retrospectively reviewed.

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Article Synopsis
  • The study analyzed hospitalized COVID-19 patients in Turkey, focusing on their characteristics and factors contributing to severe pneumonia.
  • Out of 1,013 patients, the majority were males (57.6%) with a mean age of 53.7; common symptoms included cough, fatigue, and fever, and 84.9% had pneumonia.
  • Age, blood pressure, and specific lab results (like CRP and LDH levels) were identified as key indicators of severe pneumonia, emphasizing their importance in patient evaluation.
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Introduction: Healthcare workers (HCWs) are at the forefront of the fight against coronavirus. The purpose of this study was to evaluate COVID-19 phobia levels of HCWs of a pandemic hospital and explore associated factors.

Materials And Methods: This was a descriptive cross-sectional study conducted on HCWs employed in a pandemic hospital.

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Background: CoronaVac, an inactivated whole-virion SARS-CoV-2 vaccine, has been shown to be well tolerated with a good safety profile in individuals aged 18 years and older in phase 1/2 trials, and provided a good humoral response against SARS-CoV-2. We present the interim efficacy and safety results of a phase 3 clinical trial of CoronaVac in Turkey.

Methods: This was a double-blind, randomised, placebo-controlled phase 3 trial.

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Purpose: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis.

Methods: In our hospital, 145 cases with Siltzbach Types 2 and 3 sarcoidoses diagnosed by clinical, radiological, and histopathologic were retrospectively investigated. Perilymphatic nodules, accompanying mosaic attenuation, and interlobular septal thickening and central peribronchovascular bunch-like thickening on high-resolution computed tomography were assessed as typical.

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Objective: The aim of this study is to investigate the effect of asbestos exposure on cancer-driver mutations.

Methods: Between January 2014 and September 2018, epidermal growth factor receptor (EGFR), anaplastic lymphoma receptor tyrosine kinase (ALK), and c-ros oncogene 1 receptor tyrosine kinase gene (ROS1) alterations, demographic characteristics, asbestos exposure, and asbestos-related radiological findings of 1904 patients with lung adenocarcinoma were recorded.

Results: The frequencies of EGFR mutations, ALK, and ROS1 rearrangements were 14.

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Introduction: The aim of this study is to investigate and report on the data regarding the clinical characteristics and outcomes of healthcare workers with COVID-19 at tertiary education hospitals from Turkey.

Materials And Methods: This was a single center, retrospective, descriptive and observational study using cross-sectional data, which were collected from confirmed COVID-19 patients at a tertiary education hospital. Patients' demographic and clinical characteristics, mortality rates, and the factors associated with hospitalization were analyzed.

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Setting: Although endobronchial ultrasonography-transbronchial needle aspiration (EBUS-TBNA) has a well-known place in the staging and diagnosis of lung cancer, the place of EBUS is not clear in the diagnosis of benign diseases, especially in countries with a high prevalence of tuberculosis.

Aim: The aim of this study is to investigate the diagnostic efficacy of EBUS-TBNA in benign diseases in a population with a high prevalence of tuberculosis.

Material And Methods: Between October 2011 and March 2018, 1077 EBUS-TBNA was applied.

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Introduction: Brain metastasis prevalence is higher in patients with positive epidermal growth factor receptor (EGFR) mutation, anaplastic lymphoma kinase (ALK) and C-ROS oncogene 1 (ROS-1) fusion change in lung adenocarcinoma.

Objectives: The purpose of our study is to investigate the relation between the genetic change type and the initial distant metastasis in stage IV lung adenocarcinoma patients with genetic changes.

Methods: The study was conducted between January 2007 and December 2018 in a retrospective fashion with patients who had lung cancer diagnosed as stage IV adenocarcinoma.

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Background/aim: The NoSAS score is a new tool for the identification of high-risk patients for sleep-disordered breathing (SDB). The aim of this study was to validate the NoSAS score in a sleep clinical population in Turkey and compare its performance with the Epworth Sleepiness Scale (ESS), STOP-Bang, and Berlin questionnaires for high-risk SDB.

Materials And Methods: This was a retrospective study.

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Article Synopsis
  • - The study aimed to evaluate the effectiveness and availability of smoking cessation outpatient clinics (SCCs) in Turkey, highlighting a rapid increase in their numbers.
  • - Researchers contacted 305 clinics and found that 183 were reachable, with 146 successfully participating in a questionnaire. A significant majority of physicians (85.6%) had received smoking cessation training, yet only a quarter of the clinics had tobacco control members.
  • - The findings indicated that while chest disease specialists primarily handle smoking cessation, improving both the quality of services and adherence to standards is crucial as the number of clinics continues to rise.
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Introduction: There is limited evidence about the prognostic value of FDG-PET/CT metrics in small cell lung cancer (SCLC) patients staged with TNM staging system.

Objectives: The aim of this study is to examine the prognostic value of pretreatment FDG-SUV in patients with SCLC staged with 8th TNM staging system.

Methods: A total of 344 (292 male) SCLC patients with pretreatment FDG- PET/CT were included.

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Purpose: In patients with nonsmall cell lung cancer (NSCLC), the effect of age on adjuvant chemotherapy (CT) after primary surgical treatment is controversial. The aim of this study was to investigate the effect of age and other clinical variables on survival in NSCLC patients who received adjuvant CT.

Materials And Methods: NSCLC patients who underwent primary resection and received adjuvant CT between January 2012 and January 2016 were included in the study.

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Background: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) have been shown to be prognostic markers in various types of cancers. In this study, we retrospectively investigated the prognostic role of NLR and PLR in stage III non-small cell lung cancer patients (NSCLC) treated with concurrent chemoradiotherapy (CCRT).

Materials And Methods: Seventy-nine stage III NSCLC patients treated with definitive CCRT were retrospectively evaluated.

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Introduction: Pulmonary thromboembolism (PTE) is a clinical condition that can result in sudden death. Computed tomography pulmonary angiography (CTPA) is the most sensitive imaging technique for the diagnosis of PTE. Filling defects in the pulmonary veins, which can be identified in areas adjacent to PTE, have been named the 'pulmonary vein sign' (PVS).

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Introduction: The present study was designed to evaluate inhaler techniques and patient satisfaction with fixed-combination budesonide/formoterol dry-powder inhaler chronic obstructive pulmonary disease (COPD) in Turkey in real-life clinical practice.

Patients And Methods: A total of 442 patients with COPD [mean (SD) age: 63.2 (10.

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Background: Neuron-specific enolase (NSE) is the most sensitive tumor marker for small-cell lung carcinoma (SCLC) at the time of diagnosis. The main purpose of this study was to review the usefulness of serum NSE level as a prognostic factor in patients with SCLC and to determine the correlation between the NSE level and the stage of disease and response to chemotherapy.

Methods: In this prospective study, patients with SCLC were evaluated for response to chemotherapy, survival without disease progression, and overall survival.

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