Hypercalciuria and hematuria in juvenile rheumatoid arthritis.

Objective: To investigate the frequency of hypercalciuria and the relationship between hypercalciuria and hematuria in patients with juvenile rheumatoid arthritis (JRA).

Methods: Twenty-eight children with JRA were studied, as well as 10 patients with acute arthritis unrelated to JRA and 14 healthy children as control groups. Cases with urinary calcium excretion (UCE) >4 mg/kg/day were considered hypercalciuric.

Erythromelalgia associated with hypertension and leukocytoclastic vasculitis in a child.

Erythromelalgia is an acrocyanotic rheumatic disease presenting with erythema, and pain and a burning sensation in the hands and feet; it is rarely encountered during childhood. Hot or warm conditions may precipitate pain and erythema in the extremities and the symptoms may regress upon the application of cold water. The disease is usually secondary to other systemic diseases in adults.

Superior vena cava syndrome as a result of thrombosis in a child with nephrotic syndrome.

A three-year-old nephrotic girl is presented with vena cava superior syndrome. Angiography showed obliteration of the distal ends of both axillary veins and echocardiographic examination revealed a mobile mass in the right atrium. A thrombus originating from the vena cava superior with a stalk extending to the right atrium was surgically removed.

Tubular markers in children with insulin-dependent diabetes mellitus.

The aim of the present study was to investigate the prevalence of tubular dysfunction and to assess the clinical significance of low-molecular-weight proteinuria and enzymuria in children with insulin-dependent diabetes mellitus (IDDM). N.acetyl-beta-D-glucosaminidase (NAG) and beta-microglobulin (beta 2 M) excretion was determined in 52 children with insulin-dependent diabetes mellitus and 28 controls.

Vasculitis in familial Mediterranean fever.

Objective: To evaluate the frequency of vasculitis, mainly in the forms of Henoch-Schönlein purpura and polyarteritis nodosa (PAN), and to investigate the presence of occult blood in the first stool specimens after an abdominal attack in Turkish patients with familial Mediterranean fever (FMF).

Methods: Review of the charts of 207 patients with FMF seen between 1983 and 1993 with respect to clinical vasculitis. A prospective study designed to test the presence of occult blood in the first stool specimens obtained after abdominal attack and at least one week later in 36 patients with FMF compared with healthy and diseased controls.

Bilateral inflammatory linear verrucous epidermal nevus associated with psoriasis.

Inflammatory linear verrucous epidermal nevus is a benign hyperplasia of the epidermis. Bilateral distribution of inflammatory linear verrucous epidermal nevus is an extremely rare presentation. Although inflammatory linear verrucous epidermal nevus is generally accepted as a distinct entity, it has similar clinical and histopathologic features to psoriasis, or they occasionally may overlap.

An anatomical study of the sigmoid sulcus and related structures.

Variations in the shape and size of the sigmoid sulcus were investigated in 561 temporal bones (438 isolated temporal bones, 49 skull bases and 25 half skull bases) and measurements of related structures were made. Right-left differences were analysed. The sigmoid sulcus was significantly wider (12 mm) and longer (38 mm) in the skull bases, while no differences were observed in the isolated temporal bones.

Urinary N-acetyl-beta-D-glucosaminidase and beta 2-microglobulin excretion in primary nephrotic children.

Enzymuria and low molecular weight proteinuria reflect tubular damage and dysfunction, respectively. We examined urinary N-acetyl-beta-D-glucosaminidase (U-NAG) and beta 2-microglobulin (U-beta 2M) excretion in 17 steroid-resistant and 39 steroid-sensitive children with nephrotic syndrome whose glomerular filtration rates were within the normal range. Fourteen healthy children were taken as controls.

Origin of the anterior spinal artery.

This investigation was designed to extend our present knowledge of the origin of the anterior spinal a. and is based on 80 brains of human cadavers. The anterior spinal a.

The effect of zinc supplementation in experimentally induced Toxoplasma gondii infection.

The effect of zinc added diet on cellular immunity in toxoplasmosis was investigated on 50 male wistar albino rats. Total lymphocyte CB8 count were found higher in the infected group when compared to the control group (P < 0.001).

Chest and mid-arm circumferences: identification of low birth weight newborns in Turkey.

The present study was performed to find out which anthropometric measurement(s) could efficiently be substituted for weight to detect neonates with low birth weight at birth. A total of 874 neonates, between 32 and 43 weeks of gestational age were measured within 24 h of birth to interpret the validity of anthropometric measurements. Low birth weight was observed in 10 per cent of the neonates.

Tay-Sachs disease: a case report.

Tay-Sachs disease (GM2 gangliosidosis I) is an autosomal recessive lysosomal-storage disorder confined to the central nervous system, resulting from deficiency of hexosaminidase A. The case presented is of a twelve-month-old girl brought to the hospital because of mental-motor deterioration and convulsions. She was the child of first cousins and had a history of the deaths of two siblings with the same manifestations.

Primary deep venous septic thrombophlebitis in a child.

We describe a 12-year-old boy in whom primary Staphylococcus aureus thrombophlebitis of the femoral and iliac veins developed without history of trauma and with no association with acute osteomyelitis. The patient responded to therapy with intravenously administered antibiotics for 6 weeks, although oxacillin-associated hepatitis developed during the course of treatment.

Clinical significance of fungi isolated from cerebrospinal fluid in children.

We reviewed the isolation of fungi from cerebrospinal fluid (CSF) cultures at Texas Children's Hospital during the past 6 years to evaluate the significance of a positive culture and to identify potential risk factors. Thirty-seven fungal isolates were recovered from 23 patients representing 2% of all 1498 positive CSF cultures for the study period. Candida species accounted for 94.

Meningitis due to parainfluenza virus type 3: report of two cases and review.

We report the cases of two infants with meningitis due to parainfluenza virus type 3. This is the first time that documented clinical and laboratory details have been reported for a 1-month-old infant with meningitis due to parainfluenza virus type 3 (our second case). We reviewed the literature and determined that CNS involvement by parainfluenza virus type 3 appears rare.

Comparison of children and adults with tuberculous meningitis in Elaziğ, Turkey.

Retrospective evaluation of 16 cases of tuberculous meningitis revealed that BCG vaccination and tuberculin positivity were rare in pediatric as well as adult patients. Children with disease had developmental retardation and a high rate of maternal illiteracy as compared to normal controls.

Problems in running a tuberculosis dispensary in a developing country: Turkey.

Declining use of the services of local dispensaries has often been suggested as a significant factor in the rising trend of tuberculosis in Turkey after 1970. Data confirming this view were insufficient until this study, which consists of an evaluation of the records of 51,086 subjects seen by the tuberculosis dispensary in Elaziğ between 1985-1989. We found that, despite an expected yearly population increase, there were no significant differences in the numbers of diagnostic and follow-up procedures as well as preventive and therapeutic interventions recorded in different years, and that cases of active tuberculosis lost to follow-up had gradually increased.