Evaluation of the neuroprotective effect of quercetin against damage caused by gamma radiation.

Background And Objective: Radiation therapy is a routine clinical practice that has been used for a long time in the treatment of cancer patients. The most important dose-limiting organ in patients receiving radiotherapy for various conditions is the brain. The mechanisms underlying brain and pituitary gland damage caused by radiation are largely unknown.

A Randomized Comparison Between Interscalene and Combined Interscalene-Suprascapular Blocks for Arthroscopic Shoulder Surgery: A Prospective Clinical Study.

Background: To compare the analgesic effect of ISB with a combination of ISB-SSNB and patients who were given opioids with PCA without block in adult patients undergoing shoulder surgery, as measured by opioid consumption and pain intensity in the first 24 hours postoperatively.

Methods: Ninety patients who underwent shoulder surgery were randomly divided into three groups. Group I in which ISB was performed and patient-controlled analgesia (PCA) was inserted, Group II with; ISB and SSNB combined, and PCA was inserted, and Group III where; only PCA was used.

Curcumin Attenuates Nonylphenol-Induced Toxicity In Brain Development; An Experimental Study.

Objective: Nonylphenol is an alkylphenol compound that has been widely used in the industry. It has endocrine-disrupting properties. The effect of alkylphenol compounds on development has been the subject of a limited number of studies.

The effect of playing music and mother's voice to children on sedation level and requirement during pediatric magnetic resonance imaging.

Background: Magnetic resonance imaging examinations frequently cause anxiety and fear in children. The objective of this study was to investigate the effects of listening to music sound, the mother's voice, and sound isolation on the depth of sedation and need for sedatives in pediatric patients who would undergo MRI.

Methods: Ninety pediatric patients aged 3 to 12 years who were planned for imaging in the MRI unit were randomly assigned to isolation group (Group I), musical sound group (Group II), and mother's voice group (Group III).

The effects of regular swimming exercise and melatonin on the neurons localized in the striatum of hemiparkinsonian rats.

Parkinson's disease is a progressive neurodegenerative movement disorder. We aimed to investigate the effects of regular swimming exercise and melatonin applied in the 6-Hydroxydopamine-induced Parkinson's disease rats by analysing dendritic spine of striatal neurons. Twenty-four male Wistar albino rats were used.

Clinical efficacy of ultrasound guided erector spinae plane block in patients undergoing microwave ablation.

Objectives: To compare the effect of pre-emptive erector spinae plane block (ESPB) applied before the procedure on opioid consumption during the procedure and analgesic demand and opioid consumption after the procedure.

Methods: American Society of Anesthesiologists Physical Status Classification (ASA) I-II, 30 patients, with liver tumor and planned for microwave ablation (MWA) treatment were included in the interventional radiology clinic, Erciyes University, Kayseri, Turkey, Turkey between 2021 and 2022. Patients were randomized either to the ESPB or control group.

Efficacy of stem cell-based therapies for colistin-induced nephrotoxicity.

The increase in infections with multidrug resistant bacteria has forced to return to the use of colistin, antibiotic with known nephrotoxicity. Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in regenerative medicine. This study aimed to investigate the possible protective mechanisms of the MSCs against kidney injury induced by colistin.

The neuroprotective effect of mesenchymal stem cells in colistin-induced neurotoxicity.

Colistin is an effective antibiotic against multidrug-resistant gram-negative bacterial infections; however, neurotoxic effects are fundamental dose-limiting factors for this treatment. Stem cell therapy is a promising method for treating neuronal diseases. Multipotent mesenchymal stromal cells (MSC) represent a promising source for regenerative medicine.

The effect of passive smoking on the laryngospasm rate in children sedated during the esophagogastroduodenoscopy.

Objectives: To investigate the rate of laryngospasm with sedation during the esophagogastroduodenoscopy (EGD) procedure in children exposed to passive smoking and to examine the frequency of complications due to laryngospasm.

Methods: A single-blind, prospective, observational study with a total of 518 patients evaluated according to the American Society of Anesthesiologists (ASA) physical status as classification I-II, aged between 1-18 years, and planned to undergo an EGD procedure, were included. Age, gender, weight, ASA assessment, exposure to smoking (the mother, the father, both parents were smokers, or not exposed to smoking), drug doses used in sedation, and anesthesia-related complications, such as cough, decrease in oxygen saturation, and laryngospasm were recorded.

Effectiveness of erector spinae plane block in patients with percutaneous nephrolithotomy.

Background: Percutaneous nephrolithotomy operation is a minimally invasive surgical procedure for the treatment of kidney stones.

Aim: This study aimed to evaluate the effectiveness of ultrasound-guided erector spinae plane block (ESPB) on analgesic consumption in patients who underwent percutaneous nephrolithotomy.

Subjects And Methods: The data of 60 cases who underwent percutaneous nephrolithotomy operation between 01.

Balloon Laryngoplasty for Pediatric Subglottic Stenosis: A 5-year Experience.

Objective: The objective of this study was to present our experience and evaluate our results of endoscopic balloon laryngoplasty (BL) in children with subglottic stenosis (SGS) at a pediatric tertiary center over a 5-year period.

Methods: This study reviewed 41 pediatric patients diagnosed with acquired SGS who had undergone BL as the primary course of treatment. Cases were analyzed for details including patient demographics, SGS grade and length, timing and the type of surgery, presence of tracheostomy, comorbidities, postoperative management, complications and outcomes of balloon dilatation.

Platelet-rich plasma for laryngotracheal reconstruction: an experimental study.

Objectives/hypothesis: This study was designed to evaluate the graft healing effect of topical application of platelet-rich plasma (PRP) for laryngotracheal reconstruction (LTR) in a rabbit model.

Study Design: It is a prospective randomized control animal study.

Materials And Methods: Sixteen healthy New Zealand White rabbits were assigned to two groups of eight animals each.

Thermally Treated Graphene Oxide/Polyacrylonitrile Based Electrospun Carbon Nanofiber Precursor.

Graphene oxide (GO) included polyacrylonitrile (PAN) composite electrospun nanofiber webs were fabricated, and thermal oxidation of PAN/GO composite nanofibers were performed at different temperatures (25, 250, 280, and 300 °C) for different time intervals (0, 1 and 3 h.) to investigate the oxidation process of PAN/GO nanofibers. The thermal oxidation process of PAN has a complex mechanism through the cyclization and dehydrogenation steps.

Xylitol treats nasal mucosa in rhinitis medicamentosa: an experimental rat model study.

Objective: Rhinitis medicamentosa is drug-induced rhinitis which occurs by prolonged and overdose usage of topical nasal decongestants. There is not much of treatment choice rather than nasal steroids. In this pathological study, we have been aimed to represent the healing effects of xylitol on damaged nasal mucosa due to rhinitis medicamentosa.

A Life Threatening Subglottic and Mediastinal Hemangioma in an Infant.

Subglottic and mediastinal hemangioma are rare benign vascular tumors of childhood. They cause potentially life threatening condition which requires intervention. Several therapeutic options have been described in the literature with varying degrees of success and complications.

Predictive fiberoptic endoscopic findings of upper airway in children with allergic rhinitis.

Objective: To determine predictive fiberoptic findings of upper airway in children with allergic rhinitis.

Method: 129 children had fiberoptic evaluation of nasal cavity, pharynx and larynx. They were divided into allergic rhinitis group and normal group based on skin prick test results.

Neuroprotective Effects of Lacosamide in Experimental Traumatic Spinal Cord Injury in Rats.

Aim: To evaluate the effects of lacosamide on traumatic spinal cord injury (SCI) in rats.

Material And Methods: A total of 28 male Wistar albino rats, each weighing 300-350 g, were included. They were randomly assigned to four groups.

Comparison of myotoxic effects of levobupivacaine, bupivacaine and ropivacaine: apoptotic activity and acute effect on pro-inflammatory cytokines.

We investigated the myotoxic effects of bupivacaine, ropivacaine and levobupivacaine on rat skeletal muscle and compared its apoptotic activity and acute effects on pro-nflammatory cytokines. We divided 40 Wistar albino rats into four equal groups. Rats were injected intramuscularly with 0.

[The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint].

Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.

Materials And Methods: The animals were allocated into two groups each containing 20 rabbits.

Serum endocan level and the severity of spinal cord injury.

Objective: To determine whether the endocan level may be related to the severity of spinal cord injury.

Background: Several biomarkers were evaluated for this purpose, but endocan has never been studied before. It is correlated to endothelial dysfunction and ischemia, which are the characteristics of spinal cord injury in most cases.

Oxidative stabilization of polyacrylonitrile nanofibers and carbon nanofibers containing graphene oxide (GO): a spectroscopic and electrochemical study.

In this study, a precursor for carbon nanofibers (CNF) was fabricated via electrospinning and carbonized through a thermal process. Before carbonization, oxidative stabilization should be applied, and the oxidation mechanism also plays an important role during carbonization. Thus, the understanding of the oxidation mechanism is an essential part of the production of CNF.

Routine airway surveillance in pediatric tracheostomy patients.

Objectives: The aim of this study is to review airway findings in children with tracheostomies who underwent surveillance direct laryngoscopy and bronchoscopy (DLB) to determine the yield of routine airway evaluation in these patients.

Study Design: Retrospective chart review at tertiary referral children's hospital.

Methods: A retrospective chart review was conducted of all of the children with tracheostomies who underwent DLB after tracheostomy between 1984 and 2015.

Microbiology of the Upper and Lower Airways in Pediatric Cystic Fibrosis Patients.

Objective To evaluate the microbiology of the upper and lower airways in pediatric cystic fibrosis (CF) patients who underwent sinus surgery. Study Design Retrospective case series with chart review. Setting Tertiary care children's hospital.

Characterizing mortality in pediatric tracheostomy patients.

Objectives/hypothesis: To assess the longitudinal risk of death following tracheostomy in the pediatric age group.

Study Design: Retrospective cohort study.

Methods: Hospital records of 513 children (≤18 years) at a tertiary care children's hospital who underwent tracheostomy between 1984 and 2015 were reviewed.

Stepwise Removal of the Fused Midline Parietal Bone to Avoid Superior Sagittal Sinus Injury in Infants with Sagittal Synostosis.

This work describes a simple technique for the safe removal of the midline parietal bone with the synostotic sagittal suture in infants with sagittal synostosis to avoid dural tearing and bleeding from the superior sagittal sinus. The technique consists of stepwise removal of the midline parietal bone in three pieces instead of one piece, starting with the anterior one-third midline bone being safely freed from the underlying dural sinus and then transversely cut using a craniotome. The step is repeated twice for the middle and distal one-third of the bone respectively.