Publications by authors named "Ozge Beyazcicek"

Article Synopsis
  • - Cardiovascular diseases, particularly myocardial infarction (heart attack), are the leading cause of global mortality, prompting research into potential treatments like Momordica charantia (MC), known for its antioxidant and anti-inflammatory effects.
  • - This study involved 49 male rats divided into seven groups to assess the impact of MC on heart health after inducing heart attacks using isoprenaline, with positive changes in various cardiac biomarkers and electrocardiogram (ECG) readings observed in MC-treated groups.
  • - Results demonstrated that MC administration significantly reduced harmful biomarker levels (e.g., CK-MB, TNF-α) and normalized ECG abnormalities, suggesting that MC has protective effects on heart health during myocardial infarction.
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Aims: Myocardial infarction (MI) is among the main public health problems in the world. This atherosclerotic cardiovascular disease (ASCVD), which seriously endangers human health, progresses to cause heart failure and myocardial fibrosis with a poor prognosis. The gut microbiota plays an important role in health and disease, including obesity and ASCVD.

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Article Synopsis
  • - "Pod-based" e-cigarettes like JUUL are popular in the U.S. and utilize nicotine salts, but their effects on cells are not well understood.
  • - Research involved exposing specific cells to JUUL e-liquids, assessing cell viability and calcium signaling, revealing significant cytotoxicity and increased cytoplasmic calcium, especially with "Mint" flavor.
  • - Findings suggest nicotine salt-based e-liquids can harm cells and alter calcium levels, indicating potential lung toxicity, especially with certain flavors, warranting further investigation.
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Objective: To investigate the effects of thymoquinone (TQ) in a penicillin-induced epilepsy model in rats.

Methods: This experimental study included 56 adult male Wistar rats. Experiments were performed in the Research Laboratory of the Department of Physiology, Medical School, Duzce University, Duzce, Turkey, between October 2013 and December 2014.

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