Publications by authors named "Ozge Altug Gucenmez"
Objectives: This study aimed to evaluate the risk of tuberculosis (TB) disease in children receiving biological agents for rheumatologic diseases, focusing on appropriate screening tests in a high-priority country for TB control.
Patients And Methods: One hundred nine children (56 females, 53 males; range, 3.4 to 16.
Introduction: Although inspiratory muscle training (IMT) has proven effective in adult rheumatic diseases, its impact on juvenile idiopathic arthritis (JIA) remains unexplored. The present study aimed to investigate the effects of IMT in children with JIA.
Methods: Thirty-three children (13-18 years) with JIA were divided into two groups as exercise (n = 17) and control (n = 16).
Background: Fatigue is a common problem in pediatric rheumatic diseases and is associated with poor quality of life. However, no validated methods are available to measure fatigue in adolescents with familial Mediterranean fever (FMF). The aim of the study was to establish validity and reliability for the child self-report PedsQL Multidimensional Fatigue Scale (PedsQL-MFS) and to investigate the effects of physical characteristics, diseaserelated characteristics, sleep quality/duration, and the amount of physical activity on fatigue in adolescents with FMF.
View Article and Find Full Text PDFArticle Synopsis
- The study assesses the effectiveness and safety of biological drugs for treating systemic juvenile idiopathic arthritis (SJIA) to help enhance patient outcomes.
- A total of 147 SJIA patients were evaluated, with the majority receiving interleukin (IL)-1 blockers, and findings indicated that anakinra led to better disease management scores within three months.
- The research highlights that biological treatments, especially anti-IL-1 and anti-IL-6 drugs, significantly improve disease activity and reduce the occurrence of macrophage activation syndrome (MAS).
Article Synopsis
- - The study aimed to assess how biological disease-modifying antirheumatic drugs (bDMARDs) affect the clinical course of COVID-19 in children with rheumatologic diseases, involving 113 pediatric patients treated at multiple centers.
- - Among the cohort, 71 patients experienced symptoms of COVID-19, with 24 requiring hospitalization, but there was no significant worsening of COVID-19 or underlying rheumatic conditions noted in those on bDMARDs.
- - Findings suggest that while some patients exhibited more severe symptoms, such as fever and dyspnea, more comprehensive international studies are needed for definitive conclusions regarding the interaction between bDMARD therapy and COVID-19 outcomes.
Exercise capacity has been reported to be lower in children with Juvenile Idiopathic Arthritis (JIA). Therefore, the aim was to investigate the effects of an 8-week water-based exercise program on exercise capacity in children with JIA. Forty-two children with JIA were divided into two groups as: exercise group [n = 21, water-running, moderate-intensity exercise (60-70%), two times/week], and control group (n = 21, no additional treatment other than the prescribed medication).
View Article and Find Full Text PDFAim: Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease with recurrent fever and serositis episodes. In recent years, some cases with FMF were reported with gastrointestinal involvement without amyloidosis, vasculitis and inflammatory bowel disease (IBD). It is not yet known whether gastrointestinal involvement is a part of the disease or not.
View Article and Find Full Text PDFAltuğ-Gücenmez Ö, Makay B, Kaçar A, Ünsal E. Evaluation of restless legs syndrome and growing pains in children with familial Mediterranean fever. Turk J Pediatr 2018; 60: 159-164.
View Article and Find Full Text PDFObjectives: This study aims to evaluate the publication rates and features of the abstracts related to pediatric rheumatology presented in European League against Rheumatism 2009 congress.
Patients And Methods: A systematic search was performed to find full-text publications of abstracts related to pediatric rheumatology in European League against Rheumatism 2009 congress. Full-text publication rate, the elapsed time between presentation and full-text publication, type of the disease in the studies, distribution of abstracts and full-texts according to countries, journals, and presentation types were investigated.
Objective: Patients with enthesitis-related arthritis (ERA) were less likely to achieve and sustain inactive disease than children with other subtypes of juvenile idiopathic arthritis. The aim of this study was to evaluate the effect of increased body mass index (BMI) on clinical features of the disease and to investigate whether being overweight or obese limits the possibility of achieving clinically inactive disease in patients with ERA.
Methods: The hospital charts of 72 patients with ERA were reviewed.
Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis of childhood. Gastrointestinal (GI) bleeding is one of the major complications of HSP. The blood neutrophil-to-lymphocyte ratio (NLR) is identified as a potentially useful marker of clinical outcome in inflammatory diseases.
View Article and Find Full Text PDFPotential predictors of relapse after treatment of asthma exacerbations in children.
Ann Allergy Asthma Immunol
April 2014
Background: Knowledge of factors that affect relapse will allow close monitoring of patients at risk, resulting in a decreased rate of readmission to the emergency department.
Objective: To determine risk factors associated with relapse within 7 days after treatment of asthma exacerbations in children.
Methods: This was a multicenter, prospective study of children with asthma attacks.