Does immunosuppressive treatment ameliorate morphology changes in encapsulating peritoneal sclerosis?

Encapsulating peritoneal sclerosis (EPS) is a clinical syndrome associated with ileus symptoms and irreversible sclerosis of the peritoneal membrane. Inflammation, fibrosis, and neoangiogenesis are the main features of the pathophysiology. No evidence-based therapy is currently available for EPS.

Effectiveness of tacrolimus in high-risk limbal allo-graft transplantation.

We evaluated the efficacy and safety of tacrolimus in prevention of allograft rejection in high-risk allo-limbal grafts. Six eyes of six patients with severe limbal stem cell deficiency were included. All patients were started 0.

Repair of anterior staphyloma with dehydrated dura mater patch graft.

A case of postoperative large anterior staphyloma of the sclera was treated with a dehydrated cadaveric dura mater patch graft. Structural integrity of the globe and a good cosmetic result were obtained after the surgery. During the follow-up of 2 years, no recurrence of staphyloma developed.

Evaluation of serum resistin levels in patients with ocular and non-ocular Behçet's disease.

Background: Resistin, a recently identified adipocytokine, has been found to play an important role in inflammation and the processes of inflammation-related diseases. Serum resistin levels in patients with Behçet's disease (BD) have not yet been investigated. We aimed to evaluate the relation between resistin and interleukin-6 (IL-6) in Behçet patients with or without ocular involvement and in normal controls.

Soluble endothelial protein C receptor levels in Behçet patients with and without ocular involvement.

Background: The protein C system is an important natural anticoagulant mechanism. Endothelial cell-activated protein C receptor (EPCR), which was discovered at the surface of endothelial cells, binds protein C and enhances its activation. The soluble form of EPCR (sEPCR) has been detected in plasma.

Intravenous methylprednisolone pulse therapy for acute posterior segment uveitis attacks in Behçet's disease.

We evaluated the efficacy and safety of high-dose intravenous methylprednisolone (1 g x 3 days) pulse therapy followed in the management of acute posterior segment uveitis attacks in 25 patients with Behçet's disease. High-dose intravenous methylprednisolone pulse therapy may be beneficial in the prompt control of severe ocular inflammation and in preventing visual loss.

Penetration of topically applied tacrolimus into the aqueous humor in Behçet's disease.

We investigated the concentration of tacrolimus in aqueous humor, and serum of patients with ocular Behçet's disease after topical application in 11 patients. All received 1 drop of isotonic tacrolimus solution 0.3% every 6 hours for 3 days.

Serum leptin levels in patients with ocular and nonocular Behçet's disease.

Aims: To investigate serum leptin levels in Behçet's patients with or without ocular involvement compared with healthy subjects and the relationship between serum leptin and uveitis activity in patients with ocular involvement.

Methods: Fifty-seven patients with Behçet's disease and 20 healthy control subjects were included in this study. While 27 patients had ocular involvement (18 had acute uveitis, 9 had inactive ocular involvement), 30 did not have ocular disease.

Aqueous humor and serum penetration of tacrolimus after topical and oral administration in rats: an absorption study.

Purpose: To investigate the penetration of tacrolimus to the aqueous and serum after topical and oral administration.

Methods: Thirty Wistar rats were divided into three groups. In the first group (n = 12), a single dose of 0.

Intravitreal triamcinolone acetonide in the management of cystoid macular edema in Behçet's disease.

Purpose: To determine the efficacy of intravitreal triamcinolone acetonide (ivTA) injection in the management of cystoid macular edema (CME) due to uveitis in patients with Behçet's disease.

Methods: Ten eyes of seven patients with CME associated with Behçet's disease were included in the study. A quantity of 4 mg of triamcinolone acetonide was injected intravitreally in all of the eyes.

Contact lens fitting for keratoconus after Intacs placement.

Purpose: To describe a patient with keratoconus who underwent Intacs surgery to one eye with an unsatisfactory result and refused to undergo an Intacs removal procedure.

Methods: Case report.

Results: The patient's eye was fitted with a soft contact lens for visual rehabilitation 5 months after Intacs placement.