Inflammatory biomarkers derived from whole blood cell count in atrial fibrillation patients.

Aim    This study aimed to evaluate the potential relationships between atrial fibrillation (AF) and hematological indices, such as neutrophil / lymphocyte ratio (NLR), mean platelet volume (MPV), platelet / lymphocyte ratio (PLR), mean platelet volume / platelet (MPV / PLT), neutrophil / monocyte ratio (NMR), lymphocyte / monocyte ratio (LMR), systemic immune inflammation index (SII, platelet x neutrophil / lymphocytes), and monocyte / high-density lipoprotein ratio (MHR), that can be obtained from the complete blood count (CBC test).Material and method    This retrospective study included 150 patients aged 40-80 yrs who were diagnosed with AF, and 91 age- and gender-matched controls. Hematological indices and inflammation markers were evaluated.

Exogenous Apelin-13 Administration Ameliorates Cyclophosphamide- Induced Oxidative Stress, Inflammation, and Apoptosis in Rat Lungs.

Background: Apelin-13 is an endogenous adipocytokine known for its antioxidant, antiinflammatory, and antiapoptotic properties.

Objective: We aimed to investigate the possible protective effects of exogenous Apelin-13 administration on oxidative stress, inflammation, and apoptosis induced by the cytotoxic agent cyclophosphamide (CP) in the lungs.

Methods: Twenty-four male Wistar albino rats were divided into four groups: Control (saline), CP (200 mg/kg), Apelin-13 (10 μg/kg/day), and CP+Apelin-13.

The Effects of Curcumin on Mechanical Functions and Cardiac Contractility in Isolated Rat Hearts.

Objective: Curcumin is a bioactive compound that has well-known pharmacological activities. Numerous studies have shown that curcumin provides potential cardiovascular benefits through a variety of mechanisms.The present study aims to discuss different concentrations of curcumin's impact on mechanical functions and cardiac contractility in isolated perfused rat hearts.

Effect of Skiing on Physical Performance, Pain, and Quality of Life Based on Gender.

Context: Identifying gender-specific differentiation in each sport type is significant. In this way, sport- and gender-specific gains can be predicted. Therefore, this study aimed to examine the effects of skiing on physical performance, pain, quality of life, and gender-based differentiation.

The protective effect of apelin-13 on cardiorenal toxicity induced by cyclophosphamide.

Cyclophosphamide is a chemotherapeutic drug that is widely used in the clinic and can cause multi-organ toxicity. Apelin-13 is an endogenous adipocytokine with antioxidant properties. Therefore, this study investigated the possibility of apelin-13 being a potential therapeutic agent on cardiac toxicity and nephrotoxicity caused by cyclophosphamide.

Effect of omentin on cardiovascular functions and gene expressions in isolated rat hearts.

Objective: Omentin is a recently identified novel adipocytokine mainly expressed in the epicardial adipose tissue. Although it has favorable effects on cardiovascular disease, the impact of omentin on the hearts is still an understudied issue. The aim of the present study was to investigate the possible effects of omentin on isolated rat heart.

The Effect of Chemerin on Cardiac Parameters and Gene Expressions in Isolated Perfused Rat Heart.

Background: Chemerin is a novel chemoattractant adipokine expressed in cardiovascular system, and its receptor has been detected in the epicardial adipose tissue.

Aims: To determine the effects of chemerin on the cardiac parameters and gene expressions in the isolated perfused rat heart.

Study Design: Animal experiment.

Erythropoietin Protects the Kidney by Regulating the Effect of TNF-α in L-NAME-Induced Hypertensive Rats.

Background/aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-α plays a major role in inflammation and also depresses the synthesis of erythropoietin, which exerts protective effects on tissue; however, the mechanism is still unclear.

Bilateral Coats' Disease Combined with Retinopathy of Prematurity.

Purpose. To report a case of bilateral Coats' disease combined with retinopathy of prematurity (ROP). Case.

Prevalence of nonclassic congenital adrenal hyperplasia in Turkish children presenting with premature pubarche, hirsutism, or oligomenorrhoea.

Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder. In the present work, our aim was to determine the prevalence of NCAH presenting as premature pubarche (PP), hirsutism, or polycystic ovarian syndrome (PCOS) and to evaluate the molecular spectrum of CYP21A2 mutations in NCAH patients.

Hypotensive effects of carvacrol on the blood pressure of normotensive rats.

Carvacrol is the major compound of essential oils of many plants, ethnomedically used for centuries but there were no detailed investigations on its action on the cardiovascular system. The aim of our study was to investigate the role of carvacrol on the cardiovascular functions of anesthetized rats and in vitro of isolated rat aorta. Carvacrol (100 microg/kg, I.