Anoxybacillus flavithermus loaded ɣ-FeO magnetic nanoparticles as an efficient magnetic sorbent for the preconcentrations of Cu(II) and Mn(II).

It was hypothesized that -iron( oxide nanoparticles (ɣ-FeO NPs) functionalized with Anoxybacillus flavithermus (A. flavithermus) as an effective magnetic sorbent for the preconcentrations of toxic metal ions. It is clear to conclude that the main novelty of this study is that ɣ-FeO NPs loaded with A.

Understanding patient preferences in anti-VEGF treatment options for age-related macular degeneration.

Purpose: (1) To investigate the relative importance of convenience (consultation frequency and injection frequency) against treatment outcomes (visual and anatomical outcomes) and out-of-pocket medical costs via a discrete choice experiment (DCE), and (2) to investigate how patient characteristics affect patient treatment preferences.

Methods: Eligibility criteria were: (1) receiving a neovascular age-related macular degeneration (nAMD) diagnosis; (2) receiving anti-VEGF treatment; (3) being ≥21 years old, and (4) being able to speak and understand English/Mandarin. Patients were presented with eight choice tasks and asked to choose between their current treatment and two hypothetical treatments that varied by six attributes: number of clinic visits in a year, number of injections in a year, vision quality, control of swelling in retina, drug labelling and out-of-pocket cost.

Late outcomes in children and adolescents with non-Hodgkin lymphoma: A single-center experience.

Background: Non-Hodgkin lymphoma (NHL) includes pathologies of different clinical courses, treatments, outcomes. Our study aims to investigate the late effects of NHL survivors (NHLS).

Materials And Methods: Among 59 NHL cases, 50 survivors completed their NHL treatment between 2003 and 2019.

Predictive value of ALDH1 and CD44 positivity for radiotherapy response and prognosis in early-stage glottic laryngeal squamous cell carcinoma.

To evaluate the predictive value of CD44 and aldehyde dehydrogenase 1 (ALDH1) expression for prognosis and radiotherapy (RT) response in patients with early-stage laryngeal cancer receiving RT. Forty-four patients with early-stage laryngeal cancer diagnosed between 2002 and 2016 were included in the study. The correlation between RT response and pre-treatment immunohistochemical ALDH1 and CD44 staining was evaluated.

Antimicrobial Effects of Nanostructured Rare-Earth-Based Orthovanadates.

The search for novel antimicrobial agents is of huge importance. Nanomaterials can come to the rescue in this case. The aim of this study was to assess the cytotoxicity and antimicrobial effects of rare-earth-based orthovanadate nanoparticles.

Characteristics of School Injuries Presenting to the Emergency Department.

 School injuries account for approximately one-fifth of pediatric injuries. We aimed to investigate the frequency and severity of school injuries among school-aged children and determine clinical diagnoses and surgery requirement data.  In this prospective study, children who were admitted to the emergency department due to school accidents over a 5-month period were included.

Diagnostic Performance of Machine Learning Models Based on F-FDG PET/CT Radiomic Features in the Classification of Solitary Pulmonary Nodules.

Objectives: This study aimed to evaluate the ability of fluorine-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) radiomic features combined with machine learning methods to distinguish between benign and malignant solitary pulmonary nodules (SPN).

Methods: Data of 48 patients with SPN detected on F-FDG PET/CT scan were evaluated retrospectively. The texture feature extraction from PET/CT images was performed using an open-source application (LIFEx).

Alternating pattern of rhino-orbital-cerebral mucormycosis with COVID-19 in diabetic patients.

Purpose: Our aim was to analyze the patients with diabetic rhino-orbital-cerebral mucormycosis that we have treated in our clinic in the last 5 years, and to reveal the altering conditions with COVID-19.

Materials And Methods: A retrospective study was conducted on 39 rhino-orbital-cerebral mucormycosis (ROCM) patients with diabetes mellitus between 2017 and 2022. The patients were divided into two groups as those associated with and not associated with COVID-19 and compared.

Factors associated with women's preferences for labor epidural analgesia in Singapore: a survey approach.

Epidural analgesia provides effective pain relief during labor. However, there is limited information on the factors associated with pregnant women's preferences for labor epidural analgesia (LEA) prior to labor onset. We performed a secondary analysis of a clinical trial to identify demographic characteristics, pain and psychological vulnerability factors associated with preferences for LEA.

Evaluation of age-related changes in middle-ear structures by wideband tympanometry.

Background: Presbycusis is bilateral sensorineural hearing loss associated with the progressive degeneration of cochlear and central auditory pathways with aging.

Aims/objectives: We aimed to reveal age-related changes in middle ear function by using wideband tympanometry (WBT).

Materials And Methods: Fifty-eight patients diagnosed with presbycusis were compared to 52 audiologically healthy participants.

Synthesis of two different zinc oxide nanoflowers and comparison of antioxidant and photocatalytic activity.

Nanoflowers are a newly developed class of nanoparticles that show flower-like structures and attract much attention due to their simple preparation methods, high stability, and increased efficiency. The aim of the study is to investigate a strong alternative to reduce the severity of infection and increase the treatment of wastewater by exhibiting biofilm inhibition in medical and environmental applications of the ZnO-NFs with two different shapes. ZnO-NFs were synthesized by two different processes hydrothermal method (named ZnO-NF1) and the precipitation method (named ZnO-NF2).

Patient Medication Preferences for Managing Dry Eye Disease: The Importance of Medication Side Effects.

Objectives: The side effects of dry eye medications can lead to medication non-adherence and, eventually, to poor outcomes. This study aimed to quantify to what extent the side effects of dry eye disease (DED) medications (burning/stinging sensation and blurring) are important to patients compared to medication benefits or costs.

Methods: Patients diagnosed with DED were recruited at a referral eye center in Singapore (n = 139).

Biological properties of hexadeca-substituted metal phthalocyanines bearing different functional groups.

In this study, a new tetra-substituted phthalonitrile (diethyl 2-(2-chloro-4,5-dicyano-3,6-bis(hexyloxy)phenyl)malonate) bearing three different substituents was synthesized and characterized. Due to the basic medium, transesterification occurred during the synthesis of the target phthalocyanines [M = Zn (II), Cu (II), Co (II), In (III), Lu (III)] in n-pentanol and the ethyl groups were replaced with pentyl groups. The biological features of the resultant compounds were studied for the first time in this study.

Efficacy and Safety of Ombitasvir/Paritaprevir/ Ritonavir + Dasabuvir ± Ribavirin Combinations in Patients with Genotype 1 Hepatitis C and Inherited Bleeding Disorders.

Background: Hepatitis C is one of the leading causes of death in patients with inherited bleeding disorders. Currently, direct-acting antiviral drugs used for the treatment of hepatitis C have become an effective and a reliable option for people with inherited bleeding disorders. The aim of this study is to report the efficacy and safety of ombitasvir + paritaprevir/ritonavir and dasabuvir combination in the treatment of hepatitis C in patients with inherited bleeding disorders.

Linear response theory of open systems with exceptional points.

Understanding the linear response of any system is the first step towards analyzing its linear and nonlinear dynamics, stability properties, as well as its behavior in the presence of noise. In non-Hermitian Hamiltonian systems, calculating the linear response is complicated due to the non-orthogonality of their eigenmodes, and the presence of exceptional points (EPs). Here, we derive a closed form series expansion of the resolvent associated with an arbitrary non-Hermitian system in terms of the ordinary and generalized eigenfunctions of the underlying Hamiltonian.

The Results of Cochlear Implantation in the Inner Ear Malformations.

Background: Cochlear implants are arguably the most successful neural prosthesis today. Cochlear implantation has several difficulties in patients with internal ear anomalies. This study was performed to analyze intraoperative, postoperative findings, and auditory performance of 55 patients who had inner ear malformations and were treated with cochlear implants at Otorhinolaryngology Department of Çukurova University Hospital.

Phase-cycled balanced SSFP imaging for non-contrast-enhanced functional lung imaging.

Purpose: To introduce phase-cycled balanced SSFP (bSSFP) acquisition as an alternative in Fourier decomposition MRI for improved robustness against field inhomogeneities.

Methods: Series 2D dynamic lung images were acquired in 5 healthy volunteers at 1.5 T and 3 T using bSSFP sequence with multiple RF phase increments and compared with conventional single RF phase increment acquisitions.

Remote schooling during a pandemic: Visibly Muslim mothering and the entanglement of personal and political.

This experimental double-conscious autoethnography narrates my navigation of remote learning after the COVID-19 outbreak between mid-March and early June 2020 as an apparent Muslim mother at a public school in upstate New York. To this end, using handwritten notes in a daily journal, I first delineated the process of becoming a visibly Muslim mother, which started earlier and reached a head after moving to the United States in 2018. In this way, using an autoethnographic style based on my experience of remote learning as a Muslim mother, I will present a dialog with feminist insights to reiterate that personal experience and cultural experience are incapable of being disentangled, that personal experience matters, and that all experience, however personal or private, is structured in a broader political and historical context.

Stem cell-based therapies for temporomandibular joint osteoarthritis and regeneration of cartilage/osteochondral defects: a systematic review of preclinical experiments.

Objectives: The aim of this systematic review was to assess the effects of stem cell-based therapies on the treatment of Temporomandibular Joint Osteoarthritis (TMJ-OA) and the regeneration of cartilage/osteochondral defects.

Methods: Data on preclinical studies evaluating the effectiveness of stem cell-based therapies for treating Temporomandibular Disorders (TMDs) were extracted from PubMed, Web of Science, and Cochrane Library and the grey literature by three independent reviewers. A manual search was performed in the databases, the reference list of review studies, and relevant journals in the field.

Development of lipid nanoparticles for transdermal loteprednol etabonate delivery.

Aim: Loteprednol etabonate (LE) is a new generation corticosteroid that is used for the treatment of inflammatory and allergic conditions of the eye. Therefore, solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were attempted to improve transdermal LE delivery for the first time.

Methods: SLN and NLC were produced by hot homogenisation and ultrasonication technique.

Is there a link between alopecia areata and gut?

Background: There may be an association between increased intestinal permeability and the progression of alopecia areata (AA).

Objective: The present study aimed to investigate the role of intestinal permeability in the etiopathogenesis of AA and its association with the severity of the disease.

Methods: Serum zonulin levels of 70 patients with AA who were not receiving any systemic treatment and of 70 healthy control subjects were measured.

A prospective cohort study assessing aggressive interventions at the end-of-life among patients with solid metastatic cancer.

Background: Many patients with a solid metastatic cancer are treated aggressively during their last month of life. Using data from a large prospective cohort study of patients with an advanced cancer, we aimed to assess the number and predictors of aggressive interventions during last month of life among patients with solid metastatic cancer and its association with bereaved caregivers' outcomes.

Methods: We used data of 345 deceased patients from a prospective cohort study of 600 patients.

Predictors of Hypothyroidism Following Empirical Dose Radioiodine in Toxic Thyroid Nodules: Real-Life Experience.

Objective: We aimed to determine the factors predicting hypothyroidism after radioactive iodine (RAI) treatment in patients with toxic adenoma and toxic multinodular goiter.

Methods: We retrospectively collected the data of 237 patients with toxic multinodular goiter or toxic adenoma who had consecutively received RAI treatment between 2014 and 2020 at 2 medical centers. Patients who received the second RAI treatment and whose medical records could not be accessed were excluded from the study.

Pericardial Effusion during Proton Therapy in a Patient with Chemorefractory Hodgkin Lymphoma.

We present a case of recurrent pericardial effusion presenting during proton therapy in a 24-year-old female receiving mediastinal treatment for classical Hodgkin lymphoma. Pericardial effusion is typically considered an event accompanying lymphoma diagnosis or as a subacute or late effect of radiotherapy. Rarely has it been described as occurring during radiation treatment with photon-based radiotherapy, let alone proton therapy.