A patient with axial spondylarthritis who experienced pancytopenia while receiving anti-TNF therapy.

Aplastic anemia is a rare and heterogeneous disease that causes pancytopenia and aplasia of the bone marrow. It is characterized by a failure of hematopoiesis. It is believed that approximately 65% of cases of acquired aplastic anemia are idiopathic.

The Evaluation of Forgivingness, Patience, Positivity and Mental Well-Being in Fibromyalgia Patients.

Objective: A versatile and comprehensive approach is required for the treatment of Fibromyalgia syndrome (FMS), which is characterized by multiple physical and psychological symptoms. Highlighting the psychopathology of FMS, might enable us choosing more suitable treatments. From these perspective, we planned to search the cha-racter strength and somepersonality traitsas Forgivingness, Patience, Positivity and Mental Well-Being, which are not searched before in FMS patients.

Previously Undiagnosed Hypophosphatemic Rickets Presenting Like Ankylosing Spondylitis in Adulthood: A case report.

Hypophosphatemic rickets (HR) is a metabolic bone disease manifesting with a wide variety of musculoskeletal symptoms. Sometimes it can mimic rheumatic diseases; also, it can be seen in the course of rheumatic diseases. In this paper, a 35-years old female patient, previously undiagnosed case of HR presenting first as Ankylosing Spondylitis will be discussed.

Spinal accessory nerve injury: eight cases and review of the literature.

The spinal accessory nerve (SAN) is the major motor supply to the trapezius and sternocleidomastoid muscles. The superficial course of the SAN in the posterior cervical triangle makes it vulnerable to injuries. The most common reason is an iatrogenic injury during surgery but other causes such as stretch or traction injury have also been reported.

Cytokine profiles in serum of patients with oral lichen planus.

Objective: Oral lichen planus (OLP) is a chronic inflammatory disorder of oral mucosa, which represents T-cell-mediated autoimmune diseases. The inflammatory response in OLP is characterized by the accumulation and expansion of T-helper 1 (Th1) lymphocytes. Several lines of evidence have suggested that a complex cytokine network plays an important role in the exacerbation and perpetuation of OLP.

Evaluation of cytotoxic T-cell activation, chemokine receptors, and adhesion molecules in blood and serum in patients with oral lichen planus.

Background: Our purpose is to study cytotoxic T-cell activation (through evaluation of CD8+CD40+ and CD8+CD154+ cells), chemokine receptors (through evaluation of CD8+CD184+ and CD8+CD195+ cells), and adhesion molecules (through evaluation of CD8+CD152+ cells) which play a part in cell activation in blood and serum samples of patients with OLP and then to compare them with healthy controls.

Methods: Thirty patients with OLP, and 30 matched healthy controls participated. The mean ages of OLP patients and controls were 51,10 ± 12,25 and 48,09 ± 11,92, respectively.

Retrospective radiological assessment of root canal treatment in young permanent dentition in a Turkish subpopulation.

Aim: To determine the technical quality of root fillings as well as the periapical status of root filled teeth and non-root filled teeth in young permanent dentitions using a retrospective analysis of orthopantomographs (OPTGs) in a Turkish subpopulation.

Methodology: Included in this study were the digital OPTGs taken as a part of diagnostic and planning procedures for all 19-year-old adolescents who attended the Faculty of Dentistry, Marmara University (Istanbul, Turkey) for the first time during the period from June 2007 to May 2009. The periapical status of all teeth and the technical quality of the root fillings were assessed by radiographic criteria.

Burning mouth syndrome and saliva: detection of salivary trace elements and cytokines.

Background: Burning mouth syndrome (BMS) is considered a syndrome with an unknown cause. Roles of various trace elements and cytokines in saliva have been implicated in the development of BMS. The aim of the present study was to compare the levels of salivary trace elements [magnesium (Mg), zinc (Zn), copper (Cu)] and interleukin (IL)-2 and IL-6, and to search for a correlation between depression/anxiety and salivary trace elements and cytokines in BMS patients and controls.

Serum cytokine and T regulatory cell levels in patients with burning mouth syndrome.

Background: Burning mouth syndrome is a disorder usually associated with an unexplained, prolonged sensation of burning inside the oral cavity. Although the etiology is unknown, neural and psychologic factors and cytokines may be implicated in the pathogenesis of burning mouth syndrome. The aim of this study was to investigate the relationship between serum cytokine and T regulatory cell levels in patients with burning mouth syndrome with regard to depression and anxiety.

Efficacy of moclobemide in burning mouth syndrome: a nonrandomized, open-label study.

Aims: To compare burning mouth syndrome (BMS) patients with age- and gender-matched controls for psychologic conditions, to analyze the effect of menstrual state on the intensity of burning, and to assess the efficacy of an antidepressant medication on the burning pain and psychologic status.

Methods: Ninety-four patients with BMS and 94 matched control subjects participated in the study. Anxiety and depression were analyzed by means of the Spielberger State-Trait Anxiety Inventory and Zung Self-Rating Depression Scale, and the severity of the burning sensation was measured by means of a visual analog scale (VAS).

Peripheral ameloblastoma: a case report.

Peripheral ameloblastoma, a rare and unusual variant of odontogenic tumour, comprises about 1% of all ameloblastomas. The extraosseous location is the peculiar feature of this type of tumour, which is otherwise similar to the classical ameloblastoma. An additional case of this infrequent tumour is described on the lingual alveolar mucosa of the right mandibular premolar region in a 60-year-old man.

Distribution and phospholipase activity of Candida species in different denture stomatitis types.

The aim of this study was to evaluate the correlation between frequency and phospholipase activity of Candida species and denture stomatitis according to Newton's classification. Seventy-five complete denture wearers were evaluated for the presence of yeasts on the palatal mucosa by culture method. In addition, the number of yeast isolates producing phospholipase and amount of this enzyme were determined using egg yolk agar plate method.

Oral-clinical findings and management of epidermolysis bullosa.

Epidermolysis bullosa (EB) is a diverse group of disorders that have as a common feature blister formation with tissue occuring at variable depths in the skin and/or mucosa. This article reports two cases of EB and review oral-clinical findings of the EB types and approaches for managing the oral-clinical manifestations. While systemic treatment remains primarily palliative, it is possible to prevent destruction and subsequent loss of the dentition through appropriate interventions and dental therapy.

Almost complete absence of the scalp and body hair in association with oligodontia and zygodactylous palmar triradii.

We describe an 18-year-old girl with a distinctive facial appearence, almost complete absence of the scalp and body hair, absence of the eyebrows and eyelashes, oligodontia, conically shaped maxillary central incisors and zygodactylous palmar triradii suggesting for syndactyly type I.

Neurinoma in the buccal mucosa.

A 14-year-old girl was referred to our clinic with a problem of a painless slow growing lesion for approximately three years. MR imaging findings of lesion was "retention cyst of the salivary gland". Controversially, the histological examination of the total excised specimen was "neurinoma" and that was inconsistent with MR findings.

Congenital hypodontia of maxillary lateral incisors in association with coloboma of the iris and hypomaturation type of amelogenesis imperfecta in a large kindred.

The dental, clinical, genetic, radiological and dermatoglyphic findings in patients from a large kindred with congenital hypodontia of maxillary lateral incisors (CHMLI) in association with coloboma of the iris (Cl) and hypomaturation type of amelogenesis imperfecta (HTAI) are presented. The pedigree of the kindred showing multiple consanguinaeous marriages and the findings of the family members with CHMLI and a family member with CHMLI, Cl and HTAI and two members with both CHMLI and HTAI suggested that the isolated CHMLI was due to an autosomal recessive gene, but, the Cl was determined by an autosomal dominant gene linked to CHMLI gene. HTAI was an autosomal recessive character linked to both CHMLI and Cl.

Antistreptolysin O, rheumatoid factor and C-reactive protein determination in patients with recurrent oral ulcer.

Recurrent oral ulcer (ROU) is a common disease whose the etiologic factors have not yet been identified. Although the autoimmune mechanism due to streptococcal antigens may be involved in this disease, serum immunoglobulins are reported to be higher than normal controls in various phases of ROU. Oral ulcers are one of the criteria in the diagnosis of some systemic diseases such as Wegener's granulomatosis, Behçet's syndrome, suppurative arthritis, Reiter's syndrome and neutropenias.

Generalized microdontia and associated anomalies: a clinical, genetic, radiologic and dermatoglyphic study.

The clinical, genetic, radiological and dermatoglyphic findings of a case showing generalized microdontia associated with an extra maxillary central incisor, hypoplastic maxilla, prognathic mandible, wide-set of the ears, hooked nose, astigmatism, camptodactyly, flexion contractures of the distal interphalangeal joints of the fingers, thinning of the fingers towards the distal end of the palm, and complete webbing of the IVth and Vth toes (syndactyly type III) and short stature were presented.