Safety and feasibility of laparoscopic adrenalectomy: What is the role of tumour size? A single institution experience.

Background: Although, there are studies in the literature having shown the feasibility and safety of laparoscopic adrenalectomy, there are still debates for tumour size and the requirement of the minimal invasive approach. Our hypothesis was that the use of laparoscopy facilitates minimally invasive resection of large adrenal tumours regardless of tumour size.

Materials And Methods: Within 7 years, 149 patients underwent laparoscopic adrenalectomy at one institution.

Increased interleukin 1 and tumor necrosis factor alpha levels after thyroid surgery.

Objective: The aim of this study was to consider levels of the proinflammatory cytokines IL-1 and TNFα after thyroid surgery.

Material And Methods: A total of 200 patients who underwent total thyroidectomy enrolled in this study. Drain fluid samples were taken.

Factors that affect the false-negative outcomes of fine-needle aspiration biopsy in thyroid nodules.

Background. The purpose of this study was to assess the factors that affect the false-negative outcomes of fine-needle aspiration biopsies (FNABs) in thyroid nodules. Methods.

Determinants of postoperative hypocalcemia in vitamin D-deficient Graves' patients after total thyroidectomy.

Background: The etiology of postoperative hypocalcemia after total thyroidectomy appears to be multifactorial, that is, postoperative transient hypoparathyroidism, low 25-hydroxy vitamin D (25-OHD) concentrations, aging, and hyperthyroidism with increased bone turnover. Our aim was to evaluate the factors responsible for postoperative hypocalcemia in euthyroid vitamin D-deficient/insufficient Graves patients who underwent total thyroidectomy at our institution.

Methods: Thirty-five consecutive patients with Graves disease treated by total thyroidectomy were included in the present study.

Predictive value of thyroid tissue density in determining the patients on whom sternotomy should be performed.

Background: Retrosternal goiter incidence rates range between 0.2% and 45% of all goiters, and sternotomy is performed in some of patients. There is no consensus for selecting the patients on whom sternotomy should be performed.

Predictive value of retroperitoneal fat area measurement for detecting metabolic syndrome in patients undergoing adrenalectomy.

Background: Visceral obesity is one of the main components of the metabolic syndrome (MetS). The retroperitoneal fat area (RFA) is part of the intraabdominal adipose mass. The aim of this clinical trial was to determine whether there is an association between the RFA measurement and MetS components in patients undergoing laparoscopic lateral transabdominal adrenalectomy.

Radio-guided excision of parathyroid lesions in patients who had previous neck surgeries: a safe and easy technique for re-operative parathyroid surgery.

Background: Several methods have been recommended to detect parathyroid lesions in patients who have previously undergone neck surgeries, including radio-guided surgery or intraoperative ultrasounds. In this study, we aimed to investigate whether the radio-guided excision of pathologic parathyroid lesions allowed us to find affected lesions in patients who had previously undergone neck operations.

Methods: This prospective study included 18 patients with primary hyperparathyroidism who had previously undergone neck surgeries.

Diagnostic value of thyroglobulin measurement in fine-needle aspiration biopsy for detecting metastatic lymph nodes in patients with papillary thyroid carcinoma.

Purpose: We aimed to compare the diagnostic value of fine-needle aspiration cytology (FNAC) and fine-needle aspiration thyroglobulin measurements (FNA-Tg) for detecting cervical lymph node metastases from differentiated thyroid carcinomas.

Methods: This prospective study included 225 patients with neck node metastases or recurrences of papillary thyroid carcinoma. From the 225 patients, 255 lymph nodes were evaluated by FNAC and FNA-Tg.

Intestinal Langerhans cell histiocytosis-like lesion in an adult presented with diverticulitis: a reactive or neoplastic condition?

The involvement of the gut by Langerhans cell histiocytosis (LCH) is very rare in adults; however this is usually observed with a disseminated disease in children. We report a 75-year-old male patient who underwent right hemicolectomy for a complicated intestinal diverticular disease. The surgical specimen revealed LCH-like proliferative lesion associated with diverticulitis.

N-butyl cyanoacrylate versus conventional suturing for fixation of meshes in an incisional hernia model.

Background: Chronic pain and related complications reported after the use of perforating fixation devices in hernia surgery have led to the use of tissue sealants. Fibrin sealant is a feasible option for mesh fixation; however data on cyanoacrylate glues are limited.

Methods: 32 Sprague-Dawley rats were divided into two groups and a 1.

Radio-guided excision of metastatic lymph nodes in thyroid carcinoma: a safe technique for previously operated neck compartments.

Background: Better follow-up of patients with papillary thyroid cancer (PTC) and more sensitive detection leads to detection of recurrences in the neck. Despite excellent outcomes, the major challenge is controlling locoregional recurrence. We aimed to investigate whether the radio-guided excision of metastatic lymph nodes makes it possible to find the affected lymph nodes in patients with previously operated neck compartments.

Evaluation of recurrent laryngeal nerve monitoring in thyroid surgery.

Aim: Thyroidectomy creates a potential risk for all parathyroid glands and nerves. Nerve identification has decreased the rates of nerve injury during thyroidectomy. Intraoperative nerve monitoring (IONM) has been used as an adjunct to the visual identification of the nerve.

The effect of retroperitoneal fat mass on surgical outcomes in patients performing laparoscopic adrenalectomy: the effect of fat tissue in adrenalectomy.

Background: Obesity and visceral fat are thought to be the most important factors influencing the technical difficulty during open and laparoscopic surgery. The authors aimed to investigate the effect of retroperitoneal fat mass on surgical outcomes in patients undergoing laparoscopic adrenalectomy.

Patients And Methods: This prospective study included 51 consecutive patients who underwent lateral transabdominal laparoscopic adrenalectomy.

Novel hemostatic devices in thyroid surgery: are they necessary in every patient performing thyroidectomy?

TThis study was conducted to compare the outcome of total thyroidectomy using novel hemostatic devices and the classic suture ligation technique. This prospective study included 195 consecutive patients undergoing total thyroidectomy between January 2008 and March 2009. The main outcomes measured were operating time, intraoperative blood loss, postoperative drainage, pain score, and postoperative complications.

Cardiovascular risk in patients with nonfunctional adrenal incidentaloma: myth or reality?

Background: It is not clear whether nonfunctional adrenal incidentaloma (NFA) increases the risk of atherosclerosis and metabolic syndrome or whether this type of adrenal tumor has been found more frequently in patients with cardiometabolic risk factors. We aimed to determine the effects of NFA on cardiometabolic risk factors and endothelial function and to compare the patients with a 1:1 cardiometabolic risk factor matched control group.

Methods: Thirty-five patients with NFA were studied, and 35 body mass index-, age-, and sex-matched subjects were regarded as group 2 controls.

The characteristics of concomitant thyroid nodules cause false-positive ultrasonography results in primary hyperparathyroidism.

Background: Concomitant thyroid nodules are the most common reason for false-positive ultrasonography (US) results in primary hyperparathyroidism. The aims of this prospective clinical study were to evaluate false-positive US results according to the characteristics of concomitant thyroid nodules and to determine which characteristics of thyroid nodules are important.

Study Design: This prospective study included 120 consecutive patients with primary hyperparathyroidism.

The change in the principle of performing laparoscopic adrenalectomy from small to large masses.

Background: Laparoscopic adrenalectomy has become the gold standard in most patients with adrenal tumors. It is unclear; however, at what size an adrenal neoplasm should be resected by means of an open or a laparoscopic approach. The aim of the present study was to compare the outcomes of laparoscopic adrenalectomy for large tumors with smaller tumors.

The impact of age, vitamin D(3) level, and incidental parathyroidectomy on postoperative hypocalcemia after total or near total thyroidectomy.

Background: Hypocalcemia caused by transient or definitive hypoparathyroidism is the most frequent complication after thyroidectomy. We aimed to compare the impact of incidental parathyroidectomy and serum vitamin D(3) level on postoperative hypocalcemia after total thyroidectomy (TT) or near total thyroidectomy (NTT).

Patients: Two hundred consecutive patients with nontoxic multinodular goiter treated by TT and NTT were included prospectively in the present study.

Risk factors of incidental parathyroidectomy after thyroidectomy for benign thyroid disorders.

Background: Incidental resection of parathyroid tissue is not uncommon during thyroidectomy and may occur even in the hands of experienced thyroid surgeons. We aimed to investigate the clinical relevance of incidental parathyroidectomy and to determine which risk factors are important for it.

Patients: Four hundred and forty consecutive patients with non-toxic multinodular goitre treated by total and near-total thyroidectomy were included prospectively in the present study.

Minimally invasive video-assisted subtotal parathyroidectomy with thymectomy for secondary hyperparathyroidism.

Background: Secondary hyperparathyroidism (sHPT) is common in patients with chronic renal failure. Bilateral cervical exploration is optimal for patients with sHPT. The aims of this clinical trial are to evaluate the feasibility of video-assisted subtotal parathyroidectomy as an alternative surgical treatment for sHPT.

Effect of thyroid gland volume in preoperative detection of suspected malignant thyroid nodules in a multinodular goiter.

Hypothesis: The detection of suspected malignant thyroid nodules by ultrasonography is associated with thyroid gland volume and tumor size.

Design: Prospective clinical trial.

Setting: A tertiary referral center.

Is timing important in thyroid reoperation?

Objective: Although it is recommended to perform completion thyroidectomy as soon as possible after the initial operation, there are no consensus guidelines about the appropriate time interval for the reoperation. The aim of the present study was to compare the postoperative complications, the amount of residual tissue, and postoperative thyroid-stimulating hormone (TSH) and thyroglobulin (Tg) levels following completion thyroidectomy that was performed at different time intervals.

Study Design: Sixty patients who had already undergone bilateral subtotal thyroidectomy for benign colloidal goitre and who were then diagnosed as having thyroid carcinomas at histopathologic examination were included in the study.

Predictive value of sonographic features in preoperative evaluation of malignant thyroid nodules in a multinodular goiter.

Background: The primary goal of ultrasonography (US) in the evaluation of a thyroid nodule is to determine its malignancy, although the diagnosis of a malignant nodule on the basis of US alone is nearly impossible. The aim of this prospective study was to evaluate the predictive value of sonographic features in the preoperative diagnosis of malignant thyroid nodules, and to determine the important features of sonography.

Methods: This prospective study included 550 consecutive patients with , thyroid nodules.

Electrocautery for cutaneous flap creation during thyroidectomy: a randomised, controlled study.

Background: Although electrocautery has been used widely in surgery, the fear of delayed wound healing and infection persists. We aimed to evaluate the risk factors for wound complications and the rate of wound complications, comparing the use of electrocautery or scissors in cutaneous flap creation during thyroidectomy.

Design: The study group comprised 239 consecutive patients scheduled for thyroidectomy.

The effect of anti-thyroid drug treatment duration on thyroid gland microvessel density and intraoperative blood loss in patients with Graves' disease.

Background: Preoperative preparation of the patient with Graves' disease (GD) is crucial to avoid intraoperative or postoperative complications associated with anesthesia or surgery. We aimed to evaluate thyroid blood flow and microvessel density in patients with GD according to antithyroid drug (ATD) treatment, preoperatively.

Method: Forty-three patients were divided into two groups according to the ATD type.