Publications by authors named "Ozan Yesiltepe"

Article Synopsis
  • Nanoemulsions are effective delivery systems for hydrophobic and hydrophilic compounds due to their low toxicity and ability to improve stability and bioavailability, particularly of glutathione (GSH) in aqueous environments.
  • The study focused on creating nanoemulsions from seed oils to enhance the stability of GSH and evaluate their hepatoprotective effects against ethanol toxicity in liver cells (THLE-2).
  • Results indicated that the nanoemulsions showed promising protective effects on the THLE-2 cell line when pretreated prior to exposure to ethanol, suggesting potential for future applications in liver protection.
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Atypical antipsychotic drugs induce hepatic toxicity. Thus, it is of importance to eliminate the side effects of these drugs. Herein we describe the preparation of nanoemulsions with a dietary supplement; wheat germ oil (WGO), to ameliorate the liver damage induced by clozapine and olanzapine.

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