Publications by authors named "Oyoo G"
Background: In this prospective cohort study the objective was to identify the socio-demographic and clinical factors that influence treatment response to disease-modifying antirheumatic drugs (DMARDs) at ambulatory multicenter rheumatology outpatient clinics. The subjects were patients with rheumatoid arthritis satisfying the American College of Rheumatology/European Alliance of Associations for Rheumatology criteria with informed consent.
Materials And Methods: Pre-coded data sheets were used to capture socio-demographic and clinical characteristics.
The rise in non-communicable diseases in Africa presents challenges for health systems that are burdened by infectious diseases. Gout is one of those diseases that has seen an increase in numbers worldwide, including Africa. Gout is commonly associated with comorbidities and mortality.
View Article and Find Full Text PDFBackground: Rheumatoid arthritis(RA) is a debilitating condition.Early diagnosis of RA can be difficult as the disease may initially be indistinguishable from Undifferentiated arthritis(UA). American College of Rheumatology criteria(ACR)is not suitable for early diagnosis as its characteristics are fulfilled when bone damage has already taken place.
View Article and Find Full Text PDFBackground: Previous investigations indicate that methotrexate, an old anticancer drug, could be used at low doses to treat malaria. A phase I evaluation was conducted to assess the safety and pharmacokinetic profile of this drug in healthy adult male Kenyan volunteers.
Methods: Twenty five healthy adult volunteers were recruited and admitted to receive a 5 mg dose of methotrexate/day/5 days.
Background: Articular manifestations have been reported in HIV infection with a prevalence ranging from 2.5 to 68%.
Objectives: To determine the prevalence, types and characteristics of articular manifestations in the anti-retroviral treatment naive HIV infected patients.
Background: Patients with diabetes mellitus are at a higher risk of lower extremity complications as compared to their non-diabetic counterparts.
Objective: To study risk factors for diabetic foot ulcer disease and stratify patients with diabetes into risk categories for foot ulceration.
Design: Cross-sectional descriptive study over five months period.
Objective: To determine the socio-demographic profiles and some clinical aspects of patients with rheumatoid arthritis (RA).
Design: Prospective, cross-sectional study.
Setting: Ambulatory out- patient clinics of Kenyatta National Hospital (KNH), a public national and referral hospital.
Osteoporosis--from hormonal replacement therapy to bisphosphonates and beyond: a review.
East Afr Med J
November 2007
Objective: To review the old, current, and emerging agents in pharmacological treatment of osteoporosis.
Data Sources: Published original research work and reviews from 1993 to 31 December 2006 were searched in English on subjects related to epidemiology, pathophysiology, diagnosis, treatment, and prevention of osteoporosis.
Study Design: Only articles that emphasise on management.
Background: Diabetic ketoacidosis is the most common hyperglycaemic emergency in patients with diabetes mellitus, especially type 1 diabetes. It carries very high mortality in sub-Saharan Africa, both in the treated patients and those who are presenting to hospital with diabetes for the first time.
Objective: To review the risk factors, mechanisms and management approaches in diabetes ketoacidosis in published literature and to discuss them in the context of why a significant proportion of patients who develop diabetic ketoacidosis in sub-Saharan Africa still have high mortality.
Objective: To describe vasculitis in HIV patients, their CD4 levels, anatomical sites affected and clinical patterns.
Design: Prospective, descriptive study.
Setting: Kisumu District Hospital and Nairobi Rheumatology Clinic between January 2002 and May 2005.
International League of Associations for Rheumatology (ILAR) is committed to promoting the care of those with musculoskeletal diseases. To further this aim, ILAR sponsors visiting professorships to countries with minimal or underdeveloped rheumatology services to promote the awareness and improve skills in the management of musculoskeletal conditions. Professor Luis Espinoza was sponsored and visited Kenya in March 2005.
View Article and Find Full Text PDFObjective: To review prevalence of rheumatic disorders in Sub-saharan Africa and in the context of current medical practice in the region assess the need for service and educational provision.
Data Sources: Medline, (English, French). Pre-Medline literature review from the 1950's (Current contents).
Objective: To analyse the underlying aetiology, precipitating factors and certain socio-demographic determinants in patients admitted to Kenyatta National Hospital, Nairobi in congestive heart failure.
Design: Cross sectional descriptive study.
Subject: All patients aged thirteen years and above of either sex consecutively admitted with clinical diagnosis of congestive heart failure.