Publications by authors named "Oyeyemi Matthew Olugbenga"
Corchorus olitorius is a vegetable plant/shrub and the leaves are very nutritious and rich in vitamins, minerals and dietary fibers. The study was carried out to identify the effects two extracts of this plant on the reproductive indices of male Wistar rats Forty-five adult male rats of about 12 weeks old, each weighing about 120g were used for this study, kept in a cage and fed with commercial rat pellets and water was given at ad-libitum. They were randomly divided into groups A, B and C of 15 rats per group.
View Article and Find Full Text PDFCadmium (Cd) is one of the most dangerous heavy metals in the world. Globally, toxicities associated with cadmium and its attendant negative impact on humans and animals cannot be under-estimated. Cd is a heavy metal, and people are exposed to it through contaminated foods and smoking.
View Article and Find Full Text PDFClofibrate, a Peroxisome Proliferator-Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride-Induced Toxicity.
Biol Trace Elem Res
March 2022
Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously found in the soil, water, and environment. Interestingly, fluoride has been extensively utilized for prevention of dental caries and tartar formation, and may be added to mouthwash, mouth rinse, and toothpastes.
View Article and Find Full Text PDFNovel antihypertensive action of rutin is mediated via inhibition of angiotensin converting enzyme/mineralocorticoid receptor/angiotensin 2 type 1 receptor (ATR1) signaling pathways in uninephrectomized hypertensive rats.
J Food Biochem
December 2020
Hypertension is the most common cardiovascular disease that affects approximately 26% of adult population, worldwide. Rutin is one of the important flavonoids that is consumed in the daily diet, and found in many food items, vegetables, and beverages. Uninephrectomy (UNX) of the left kidney was performed, followed by induction of hypertension.
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- Bisphenol A (BPA) is identified as an endocrine disrupting chemical that negatively affects the reproductive organs, while melatonin (ML) serves as a protective antioxidant against these effects.
- In a study involving adult male Wistar rats divided into four groups, those treated with BPA exhibited increased prostatic index and altered hormone levels, while concurrent administration of ML helped improve these adverse conditions.
- The study concludes that low doses of melatonin can mitigate the harmful effects of BPA on prostate health, as shown by improved hormonal balance and reduced structural damage in the prostate gland of rats.
Article Synopsis
- Aloe vera is a commonly used herb that was tested for its effects on the semen quality of West African Dwarf bucks.
- In the study, twelve bucks were divided into two groups and treated with different concentrations of Aloe vera extract over 14 days, with semen samples collected before and after treatment.
- The results showed that Aloe vera significantly decreased sperm concentration, motility, and livability while increasing sperm abnormalities, indicating it could negatively impact male fertility and breeding.