Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women.

Although breast cancer (BC) incidence is lower in African-American women compared with White-American, in African countries such as Nigeria, BC is a common disease. Nigerian women have a higher risk for early-onset, with a high mortality rate from BC, prompting speculation that risk factors could be genetic and the molecular portrait of these tumours are different to those of western women. In this study, 308 BC samples from Nigerian women with complete clinical history and tumour characteristics were included and compared with a large series of BC from the UK as a control group.

Arteriovenous malformation of the occipital lobes in a Nigerian.

Aim: To present the clinical features of arteriovenous malformations of the occipital lobe in order to assist in making a diagnosis prior to intracerebral haemorrhage.

Methods: A Sixty one year old Nigerian male patient complained of constant frontal headache for five years with associated gradual visual loss. Six months before presentation he suffered two episodes of severe headache associated with dizziness and profound visual loss.

Histopathological study of soft tissue malignancies in a teaching hospital, Sagamu, South-West Nigeria.

Background: Soft tissue malignancies constituted a heterogeneous group of rare solid tumors of mesenchymal cell origin with distinct clinical and pathological features.

Objectives: To review all the histologically confirmed soft tissue malignancies, with their age, sex distribution, and histological characteristics in Sagamu, South-West Nigeria.

Methods: A review of all the medical and pathological records and slides of histopathologically diagnosed soft tissue malignancy cases seen between January 2003 and December 2006.

Primary malignant bone tumours in Ibadan, Nigeria: an update.

Bone tumours are relatively rare compared to tumours of other sites. The frequency of primary malignant bone tumours is low in our environment, as was observed in an earlier study. The aim of this study is to update the information available on the pattern of primary malignant bone tumours at the University College Hospital (UCH), Ibadan, Nigeria.

Pattern of childhood malignant tumours in a teaching hospital in south-western Nigeria.

Objective: To document general baseline data on the patterns of childhood malignant tumours at a teaching hospital in south-western Nigeria.

Design, Setting And Participants: A retrospective study of childhood malignancy at Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria, during an 11-year period, from January 1996 to December 2006.

Results: 77 children were diagnosed with malignant tumours (an average of seven diagnoses per year); 46 were boys (60%), giving a male-to-female ratio of 1.