Publications by authors named "Oya Eralp Inan"
Article Synopsis
- The study investigates the coagulation status of dogs with canine parvoviral enteritis (CPE), a severe condition that can lead to high mortality due to systemic inflammation and multi-organ dysfunction.
- It involved 21 dogs diagnosed with CPE and 5 healthy controls, using thromboelastography (TEG) to analyze coagulation, showing significant differences in reaction times and clot dissolution rates.
- The findings suggest that TEG-derived velocity curve (v-curve) parameters could be a better method to assess coagulation in CPE cases, offering new insights for diagnosis and treatment strategies.
Sepsis/endotoxemia associates with coagulation abnormalities. We showed previously that exogenous choline treatment reversed the changes in platelet count and function as well as prevented disseminated intravascular coagulation (DIC) in endotoxemic dogs. The aim of this follow-up study was to evaluate the effect of treatment with choline or cytidine-5'-diphosphocholine (CDP-choline), a choline donor, on endotoxin-induced hemostatic alterations using thromboelastography (TEG).
View Article and Find Full Text PDFThe aim of the present study was to investigate effects of intravenous (i.v.) choline treatment on serum matrix metalloproteinases (MMP), MMP tissue inhibitors (TIMP) and immunoglobulins (Igs), and to determine if there were relations between serum MMPs/TIMPs and C-reactive protein (CRP) (as a marker of the acute phase response), immunoglobulin G and M (IgG and IgM) (as a maker of the Ig responses) and markers of organ damage such as muscular damage (creatine phosphokinase, [CPK]), liver damage (alanine aminotransferase [ALT]) and renal dysfunction (blood urea nitrogen [BUN] and creatinine, [Cr]) in dogs with endotoxemia.
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