Histological Alterations from Condyle Repositioning with Functional Appliances in Rats.

Objective: This study was designed to assess the morphological and histological alterations of the condyle of rats undergoing forward mandibular repositioning via functional appliance.

Materials And Methods: Functional appliances were mounted onto the upper jaws of rats. Morphological analysis was conducted on micro-CT images of sacrificed animals.

Management Guidelines for Traumatically Injured Teeth during Orthodontic Treatment.

This article presents a summary of incident management guidelines for traumatically injured teeth during orthodontic treatment. In addition, treatment of a 17-year-old patient with traumatic extrusion and palatal displacement of the permanent maxillary incisors while undergoing active orthodontic treatment is reported.

Incident management guidelines for an ingested orthodontic object.

Dental materials or components of orthodontics devices can fall into a patient's oropharynx, and be swallowed or inhaled. In this paper a short review of accidental foreign body ingestion/aspiration prevention, evaluation, and relevant incident management guidelines are presented. In addition, a case of an accidentally swallowed piece of archwire during a chair side procedure is reported.

The biology of TMJ growth modification: a review.

Several studies have indicated a positive response of the temporomandibular joint (TMJ) to mandibular advancement, while others have reported that TMJ adaptive responses are non-existent and negligible. Controversy continues to grow over the precise nature of skeletal changes that occur during mandibular growth modification, due to an apparent lack of tissue markers required to substantiate the precise mechanism by which this is occurring. However, evidence suggests that orthopedic forces clinically modify the growth of the mandible.

A histochemical study on condylar cartilage and glenoid fossa during mandibular advancement.

Objective: To evaluate cellular hypertrophic activities in the mandibular condylar cartilage (MCC) and the glenoid fossa (GF) during mandibular advancement in the temporomandibular joint (TMJ) of Sprague-Dawley rats, as evidenced by fibroblast growth factor 8 (FGF8).

Methods And Materials: Fifty-five female 24-day-old Sprague-Dawley rats were randomly divided into four experimental and control groups, with a mandibular advancement appliance on the experimental rats' lower incisors. The rats were euthanized on days 3, 14, 21, and 30 of the study, and their TMJ was prepared for a immunohistochemical staining procedure to detect FGF8.

The biological mechanisms of PCNA and BMP in TMJ adaptive remodeling.

Objectives: To histologically and immunohistochemically assess the pattern of expression of bone morphogenic proteins 2 and 4 (BMP2/4) and proliferating cell nuclear antigen (PCNA) in response to bite jumping appliances in the condylar cartilage and the glenoid fossa.

Materials And Methods: Fifty-five 4-week-old female Sprague-Dawley rats were randomly divided into four experimental and four control groups. Bite-jumping appliances were fitted to the experimental animals.