Publications by authors named "Owoola Azeezat Ambali"
(Guill. & Perr.) Benth. leaf abates deregulation of P53, IRS, HsD17β2, FTO, and CYP11a genes in polycystic ovarian syndrome rat.
Akingbolabo Daniel Ogunlakin Meek Oyinlola Meruwoma Princewill Obinna Ihiasota Oluwafemi Adeleke Ojo Adeyemi Abdullahi Adegoke Owoola Azeezat Ambali
J Complement Integr Med
November 2024
Article Synopsis
- - This study explored how leaf extracts could help improve symptoms of polycystic ovary syndrome (PCOS) in Wistar rats induced by letrozole.
- - Treatment with leaf extracts significantly improved hormonal balance and regularity of the estrus cycle, and showed a positive effect by reducing testosterone and increasing estradiol levels.
- - The extract also normalized several important gene expressions linked to metabolic and hormone regulation, indicating its potential as a promising treatment for PCOS.
Elemental evaluation, nutritional analysis, GC-MS analysis and ameliorative effects of J.R.Forst. & G.Forst. seeds' phytoconstituents on metabolic syndrome via approach.
Akingbolabo Daniel Ogunlakin Oluwafemi Adeleke Ojo Gideon Ampoma Gyebi Idayat Adeola Akinwumi Great Oluwamayokun Adebodun Owoola Azeezat Ambali
J Biomol Struct Dyn
December 2023
The nutritional as well as beneficial effects of the seed on metabolic syndrome complications have not been studied. In this research, the aim was to investigate the nutritional composition and beneficial effects of seeds' phytoconstituents on the core, fat mass and obesity-associated (FTO) protein and cytochrome P450 CYP11A1 domains. The elements and phytochemicals in the seed were determined through atomic absorption spectroscopy assay and gas chromatography-mass spectrometry (GC-MS) analysis, respectively.
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