Prolactin and thyrotropin response to thyrotropin-releasing-hormone in adolescent females with insulin-treated diabetes mellitus.

Prolactin and thyrotropin response to TRH and basal gonadotropins levels in blood were investigated in insulin-treated adolescent females with regular menstruation cycles (Group I) and menstruation disturbances (Group II) compared with control, healthy girls. No significant differences were found in TSH secretion after TRH administration and basal LH, FSH levels between the observed groups. Blood basal PRL levels were significantly lower in young females in Group II, and a highly increased mobilization of PRL secretion (delta % PRL)--masked hyperprolactinaemia--in all of the groups of diabetic girls was revealed.

Effects of phentolamine on serum concentrations of TSH and thyroid hormones in hemithyreoidectomized rats.

The effects of phentolamine on the concentrations of TSH and the thyroid hormones in hemithyreoidectomized (hemiTXized) rats have been examined. Phentolamine caused a decrease of TSH level in blood serum 30 min after the injection, suggesting an inhibiting effect of phentolamine on TSH secretion. Thyroxine (T4) concentration decreased after 30 min.

[Thyrotropic and thyroid hormone (T3 and T4) content in Horton' s headache patients].

In 18 men with Horton's headaches the levels of the following hormones were determined in the serum: TSH, T3 and T4. The determinations were performed during disease relapse and before starting treatment. The control group included 18 blood donors.

Clinical, hormonal and semiological data in adult men operated in childhood for hypospadias.

Examination of 16 adult men operated in childhood for hypospadias revealed signs of moderate injury of the male genital system. It appears that accessory sexual glands were mainly responsible for the observed abnormalities. Since testicular position and size, serum testosterone and FSH levels were normal it seems that hypospadias and the accompanied disturbances are connected with reduction of responsiveness of target tissues to androgen stimuli rather, than with lesion of the testicle.

Serum immunoglobulins IgG and IgM in the seminal plasma of men with normospermia, oligozoospermia, and azoospermia.

The seminal plasma of eight males with normospermia, seven with oligozoospermia, and eight with azoospermia was examined for the presence of IgG and IgM by means of double-gel immunodiffusion. IgG was present in every seminal plasma sample. The highest titers of IgG were found in azoospermic and normospermic samples, but the lowest IgG titers were seen only in normospermic samples.

Decrease of plasma somatotropin levels following thyroliberin (TRH) administration in patients with hyperthyroidism.

Thyroliberin was observed to induce a significant decrease of plasma somatotropin levels in patients with untreated hyperthyroidism, except those with very low initial somatotropin levels. These data have confirmed our previous finding where we noted that under the conditions of thyroid hormone excess thyroliberin was able to exert an inhibitory effect on somatotropin release.